ZNF198 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-56490

Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
NB100-56490
NB100-56490SS
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Species Reactivity

Validated:

Human, Canine, Primate

Predicted:

Bovine (94%), Chicken (94%), Mouse (94%), Rat (94%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all ZNF198 Antibodies »

Product Summary for ZNF198 Antibody

Immunogen

A portion of amino acids 1250-1300 of human Zinc finger protein 198 was used as the immunogen.

Reactivity Notes

Xenopus proteins (76%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ZNF198 Antibody

Western Blot: ZNF198 Antibody [NB100-56490]

Western Blot: ZNF198 Antibody [NB100-56490]

Western Blot: ZNF198 Antibody [NB100-56490] - Analysis of ZNF198 in mouse skeletal muscle lysate in the 1) absence and 2) presence of immunizing peptide using this antibody at 0.1 ug/ml.
Immunohistochemistry-Paraffin: ZNF198 Antibody [NB100-56490]

Immunohistochemistry-Paraffin: ZNF198 Antibody [NB100-56490]

Immunohistochemistry-Paraffin: ZNF198 Antibody [NB100-56490] - Analysis of human breast using this antibody at 10 ug/ml.

Applications for ZNF198 Antibody

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

10 ug/ml

Western Blot

0.1-1 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS containing 0.2% gelatin

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ZNF198

ZNF198 is a ubiquitously expressed nuclear protein whose physiological role is largely unknown. It consists of 5 N-terminal zinc finger motifs responsible for protein-protein interactions, a central proline-rich domain and C-terminal nuclear localization signal (NLS) and an acidic domain. Reciprocal chromosomal translocation involving ZNF198 and FGFR1 results in the formation of ZNF198/FGFR1 fusion kinase protein. This fusion protein is a ligand-dependent, constitutively active cytoplasmic tyrosine kinase and regulates several STAT transcription factors including STAT 1, 3 and 5. This fusion protein is an oncogenic protein and is associated with an atypical myeloproliferative disease, peripheral blood eosinophilia and T-cell leukemia/lymphoma.

Alternate Names

FIMRAMPSCLL, Fused in myeloproliferative disorders protein, MYM, Rearranged in atypical myeloproliferative disorder protein, Zinc finger protein 198rearranged in an atypical myeloproliferative disorder, zinc finger, MYM-type 2, ZNF198zinc finger MYM-type protein 2

Entrez Gene IDs

7750 (Human); 76007 (Mouse); 305913 (Rat)

Gene Symbol

ZMYM2

UniProt

Q9UBW7 (Mouse)

Additional ZNF198 Products

Product Documents for ZNF198 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for ZNF198 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.