Rabbit C-Reactive Protein/CRP ELISA Kit (Colorimetric)

Novus Biologicals, part of Bio-Techne | Catalog # KA1975

Novus Biologicals, part of Bio-Techne
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Key Product Details

Sample Type & Volume Required Per Well

Biological Sample (100 uL)

Sensitivity

1.471

Assay Range

6.25 to 200 ng/mL

View all C-Reactive Protein/CRP ELISA Kits »

Product Specifications

Assay Type

Two-site enzyme-linked immunoassay

Kit Type

ELISA Kit (Colorimetric)

Reactivity

Rabbit

Description

CRP (Rabbit) ELISA Kit is a highly sensitive two-site enzyme-linked immunoassay for the quantitative determination of CRP in rabbit biological samples.

Kit Contents for Rabbit C-Reactive Protein/CRP ELISA Kit (Colorimetric)

  • Anti-Rabbit CRP ELISA Micro Plate: Twelve removable eight (8) well micro well strips in well holder frame. Each well is coated with affinity purified anti-rabbit CRP.
  • Chromogen-Substrate Solution: One vial containing 3,3’,5,5’-tetramethybenzidine (TMB) and hydrogen peroxide in citric acid buffer at pH 3.3.
  • Diluent Concentrate (Running Buffer): One bottle containing a 5X concentrated diluent running buffer
  • Enzyme-Antibody Conjugate (100X): One vial containing affinity purified anti-rabbit CRP antibody conjugated with horseradish peroxidase in a stabilizing buffer.
  • Rabbit CRP Calibrator: One vial containing a lyophilized Rabbit CRP calibrator.
  • Wash Solution Concentrate: One bottle containing a 20X concentrated wash solution.

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: C-Reactive Protein/CRP

C Reactive Protein is a major acute phase reactant synthesized primarily in the liver hepatocytes. It is a pentraxin (cyclic pentameric protein) compound of five identical nonglycosylated subunits of 206 amino acids each (m.w. 24 kDa), that are bound noncovalently to form the physiologic CRP molecule (m.w. 117.5 kDa). C Reactive Protein mediates activities associated with preimmune nonspecific host resistance. It is opsonic, an initiator of the classical complement cascade and an activator of monocytes/macrophages. CRP also binds to several nuclear components including chromatin, histones and snRNP, suggesting that it may play a role as a scavenger during cell necrosis. Studies have revealed that among other markers of inflammation, CRP shows the strongest association with cardiovascular events. Many clinical studies demonstrated that coronary mortality among patients with unstable angina and elevated CRP is significantly higher comparing with the patients without elevated CRP. Measurements of C reactive protein (hsCRP) in the patients with ischemic heart disease provide a novel method for detecting individuals at high risk of plaque rupture.

Alternate Names

CRP

Gene Symbol

CRP

Additional C-Reactive Protein/CRP Products

Product Documents for Rabbit C-Reactive Protein/CRP ELISA Kit (Colorimetric)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Rabbit C-Reactive Protein/CRP ELISA Kit (Colorimetric)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

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