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CXCL5/ENA-78 Antibody Pair [HRP]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-79316

Novus Biologicals, part of Bio-Techne
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NBP2-79316-15Plates
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Key Product Details

Assay Type

Sandwich ELISA

Assay Range

3.91-250 pg/ml (example only; lot dependent)

Sensitivity

3.91 pg/ml (example only; lot dependent)

Reactivity

Human

Product Specifications

Description

Solid Phase sandwich ELISA for the quantitative determination of Human CXCL5/ENA-78.

Sample Volume Required

100 ul

Conjugate

HRP

Scientific Data Images for CXCL5/ENA-78 Antibody Pair [HRP]

Sandwich ELISA: CXCL5/ENA-78 Antibody Pair [HRP] [NBP2-79316]

Kit Contents for CXCL5/ENA-78 Antibody Pair [HRP]

  • Mouse Monoclonal Capture Antibody
  • Mouse Monoclonal Detection Antibody (HRP-conjugated)
  • Standard

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Storage of components varies. See protocol for specific instructions.

Background: CXCL5/ENA-78

CXCL5/Epithelial Cell-derived Neutrophil-activating Peptide (ENA-78), is a member of the CXC subfamily of chemokines. Full-length CXCL5/ENA-78 is 114 amino acids (aa) in length with a predicted molecular weight of 12 kDa. Following the removal of the signal peptide, bioactive CXCL5/ENA-78 is 78 aa in length. CXCL5/ENA-78 can be N-terminally cleaved by Cathepsin G and Chymotrypsin to CXCL5/ENA-74 (74 aa) and CXCL5/ENA-70 (70 aa), which show increased potency relative to CXCL5/ENA-78. While murine LIX was thought to be an ortholog to human CXCL5/ENA-78, genome-wide analysis and a consensus in the field suggests that human CXCL5/ENA-78 does not have a true murine ortholog. CXCL5/ENA-78 is upregulated at sites of inflammation and is expressed by multiple hematopoietic cell types, fibroblasts, endothelial cells, vascular smooth muscle cells, and adipocytes. It acts as a chemoattractant for neutrophils, has angiogenic properties, and contributes to cancer progression.

Alternate Names

CXCL5, ENA-78, ENA78

Gene Symbol

CXCL5

Additional CXCL5/ENA-78 Products

Product Documents for CXCL5/ENA-78 Antibody Pair [HRP]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CXCL5/ENA-78 Antibody Pair [HRP]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

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