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Human Matriptase/ST14 Catalytic Domain DuoSet ELISA

R&D Systems, part of Bio-Techne | Catalog # DY3946-05

R&D Systems, part of Bio-Techne
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DY3946-05

Ancillary Products Available

Key Product Details

Assay Type

Solid Phase Sandwich ELISA

Assay Range

0.781-50 ng/mL

Sample Type

Cell culture supernates, serum, and plasma
Note: Diluents for complex matrices, such as serum and plasma, should be evaluated prior to use in this DuoSet

Reactivity

Human

Human Matriptase/ST14 Catalytic Domain DuoSet ELISA Features

  • Optimized capture and detection antibody pairings with recommended concentrations save lengthy development time
  • Development protocols are provided to guide further assay optimization
  • Assay can be customized to your specific needs
  • Economical alternative to complete kits

Product Summary for Human Matriptase/ST14 Catalytic Domain DuoSet ELISA

This DuoSet ELISA Development kit contains the basic components required for the development of sandwich ELISAs to measure natural and recombinant human Matriptase. The suggested diluent is suitable for the analysis of most cell culture supernate samples. Diluents for complex matrices, such as serum and plasma, should be evaluated prior to use in this DuoSet ELISA.

Product Specifications

Assay Format

96-well strip plate (sold separately)

Sample Volume Required

100 µL

Detection Method

Colorimetric ELISA - 450nm (TMB)

Conjugate

Biotin

Label

HRP

Scientific Data Images for Human Matriptase/ST14 Catalytic Domain DuoSet ELISA

Human Matriptase DuoSet ELISA Standard Curve

Kit Contents for Human Matriptase/ST14 Catalytic Domain DuoSet ELISA

  • Capture Antibody
  • Detection Antibody
  • Recombinant Standard
  • Streptavidin conjugated to horseradish-peroxidase (Streptavidin-HRP)

Other Reagents Required


PBS:(Catalog #DY006), or 137 mM NaCl, 2.7 mM KCl, 8.1 mM Na2HPO4, 1.5 mM KH2PO4, pH 7.2 - 7.4, 0.2 µm filtered

Wash Buffer:(Catalog #WA126), or equivalent

Reagent Diluent*

Blocking Buffer*

Substrate Solution:ELISA TMB Substrate (Catalog #DY999B)

Stop Solution:2N H2SO4(Catalog #DY994)

Microplates: R&D Systems (Catalog #DY990), or equivalent

Plate Sealers:ELISA Plate Sealers (Catalog #DY992), or equivalent

*For the Reagent Diluent and Blocking Buffer recommended for a specific DuoSet ELISA Development Kit, please see the product.

Preparation and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: Matriptase/ST14

Human matriptase, encoded by the ST14 (suppression of tumorogenicity 14) gene, is also known as tumor associated differentially expressed gene 15 protein/TADG-15), epithin, and membrane-type serine protease 1/MT-SP1. Predicted to have a significant role in tumor biology, matriptase may be a novel target for anti-cancer therapy. However, expressed in most human epithelia, matriptase is also important in several physiological processes. For example, it activates prostasin to initiate a protease cascade that is essential for epidermal differentiation, and it converts a single-chain IGFBP-rp1 into the two-chain form.

Alternate Names

Epithin, MTSP1, PRSS14, SNC19, ST14, TADG-15, TMPRSS14

Entrez Gene IDs

6768 (Human); 19143 (Mouse); 114093 (Rat); 102117178 (Cynomolgus Monkey)

Gene Symbol

ST14

Additional Matriptase/ST14 Products

Product Documents for Human Matriptase/ST14 Catalytic Domain DuoSet ELISA

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human Matriptase/ST14 Catalytic Domain DuoSet ELISA

For research use only

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