Human Phospho-p70 S6 Kinase (T389) DuoSet IC ELISA

R&D Systems, part of Bio-Techne | Catalog # DYC896B-5

R&D Systems, part of Bio-Techne
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Key Product Details

Sample Type

Cell Lysates

Reactivity

Human

View all p70 S6 Kinase ELISA Kits »

Product Specifications

Detection Method

Colorimetric ELISA - 450nm (TMB)

Specificity

Please see the product datasheet

Label

HRP

Preparation and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: p70 S6 Kinase

p70 S6 kinase is a Ser/Thr kinase activated by such mitogens as EGF, IGF-I, and insulin. The S6 protein of the 40S ribosomal subunit is a major substrate of p70 S6 kinase, and its phosphorylation upregulates the translation of mRNAs containing an oligopyrimidine tract at their transcriptional start site. The activity of p70 S6 kinase is controlled by multiple phosphorylation events, with phosphorylation at T229 by PDK1 and T389 by mTOR most critical for kinase function.

Alternate Names

p70-alpha, RPS6KB1, S6K1, STK14A

Entrez Gene IDs

6198 (Human); 72508 (Mouse); 83840 (Rat)

Gene Symbol

RPS6KB1

Additional p70 S6 Kinase Products

Product Documents for Human Phospho-p70 S6 Kinase (T389) DuoSet IC ELISA

Product Datasheets

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human Phospho-p70 S6 Kinase (T389) DuoSet IC ELISA

For research use only

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