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Human IL6R ELISA Kit (Colorimetric)

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-89870

Novus Biologicals, part of Bio-Techne
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NBP1-89870

Key Product Details

Sample Type & Volume Required Per Well

Cell culture supernatant, serum, plasma (EDTA, heparin), amniotic fluid, urine (20 uL)

Sensitivity

0.01 ng/mL

Assay Range

0.08 - 5.0 ng/mL

Product Specifications

Assay Type

Sandwich ELISA

Kit Type

ELISA Kit (Colorimetric)

Reactivity

Human

Specificity

The interference of circulating factors of the immune systeme was evaluated by spiking these proteins at physiologically relevant concentrations into a human IL-6R positive serum. There was no crossreactivity detected.

Description

This kit is an enzyme-linked immunosorbent assay for quantitative detection.

Precision

Intra-Assay Precision (Precision within an assay) CV% < 1.7%

Inter-Assay Precision (Precision between assays) CV% < 2.2%

Scientific Data Images for Human IL6R ELISA Kit (Colorimetric)

Sandwich ELISA: Human IL6R ELISA Kit (Colorimetric) [NBP1-89870] - Representative standard curve for human IL-6R ELISA. Human IL-6R was diluted in serial 2-fold steps in IL-6RAssay Buffer (1x). Do not use this standard curve to derive test results. A standard curve must be run for each group ofmicrowell strips assayed.

Kit Contents for Human IL6R ELISA Kit (Colorimetric)

  • Adhesive Plate Covers
  • Aluminium pouch(es) with a human sIL-6R Standard curve (coloured)
  • Aluminium pouch(es) with a Microwell Plate coated with Monoclonal Antibody (murine) to human sIL-6R and HRP-Conjugate (anti-sIL-6R monoclonal (murine) antibody), lyophilized
  • Assay Buffer Concentrate 20x (PBS with 1% Tween 20 and 10% BSA)
  • Lyophilized Control
  • Stop Solution (1M Phosphoric acid)
  • Substrate Solution (tetramethyl-benzidine)
  • Wash Buffer Concentrate 20x (phosphate-buffered saline with 1% Tween 20)

Preparation and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Storage of components varies. See protocol for specific instructions.

Background: IL6R

Interleukin 6 (IL6) is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response. The protein encoded by this gene is a subunit of the receptor complex for IL6. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]

Alternate Names

CD126, CD126 antigen, gp80, IL-6 receptor subunit alpha, IL-6R 1, IL-6R subunit alpha, IL-6R-1, IL6RA, IL-6RA, IL-6R-alpha, interleukin 6 receptor, interleukin 6 receptor alpha subunit, interleukin-6 receptor subunit alpha, Membrane glycoprotein 80, MGC104991

Gene Symbol

IL6R

Additional IL6R Products

Product Documents for Human IL6R ELISA Kit (Colorimetric)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Human IL6R ELISA Kit (Colorimetric)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

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