Human Serpin F2/alpha 2-Antiplasmin ELISA Kit (Colorimetric)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-08193

Novus Biologicals, part of Bio-Techne
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NBP3-08193
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Key Product Details

Sample Type & Volume Required Per Well

Serum, Plasma, Cell supernatant

Sensitivity

7.5 ng/mL

Assay Range

12.5 - 800 ng/mL

View all Serpin F2/alpha 2-Antiplasmin ELISA Kits »

Product Specifications

Assay Type

Sandwich-ELISA

Kit Type

ELISA Kit (Colorimetric)

Reactivity

Human

Precision

Intra-Assay Precision (Precision within an assay) %CV < 5.06

Inter-Assay Precision (Precision between assays) %CV < 5.60

Recovery for Human Serpin F2/alpha 2-Antiplasmin ELISA Kit (Colorimetric)

Recovery

89 - 107%

Linearity

Human Serpin F2/alpha 2-Antiplasmin ELISA Kit (Colorimetric)

Scientific Data Images for Human Serpin F2/alpha 2-Antiplasmin ELISA Kit (Colorimetric)

Human Serpin F2/alpha 2-Antiplasmin ELISA Kit (Colorimetric)

ELISA: Human Serpin F2/alpha 2-Antiplasmin ELISA Kit (Colorimetric) [NBP3-08193] -

ELISA: Human Serpin F2/alpha 2-Antiplasmin ELISA Kit (Colorimetric) [NBP3-08193] - Standard Curve Reference

Kit Contents for Human Serpin F2/alpha 2-Antiplasmin ELISA Kit (Colorimetric)

  • Micro ELISA Plate (Dismountable) - 1 EA, Reference Standard - 2 vials, Concentrated Biotinylated Detection Ab (100X) - 120 uL, Concentrated HRP Conjugate (100X) - 120 uL, Reference Standard & Sample Diluent - 20 mL, Biotinylated Detection Ab Diluent - 14

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Storage of components varies. See protocol for specific instructions.

Background: Serpin F2/alpha 2-Antiplasmin

Identification in human milk of complexes of matriptase with ATIII, A1AT, or A2AP, provides evidence that the proteolytic activity of matriptase, from cells that express no or low levels of HAI-1, may be controlled by secreted serpins. Sequencing analysis revealed the presence of two alpha2-PI gene variations, both in the second half of exon 10: a frameshift mutation and a G to A transition at nucleotide 11337 in codon 407. Observational study of gene-disease association. (HuGE Navigator). Thrombin activatable fibrinolysis inhibitor and alpha(2)-antiplasmin are not markers for recanalization in patients with ischemic stroke treated with recombinant tissue-type plasminogen activator. Fibrinolysis is amplified by converting alpha-antiplasmin from a plasmin inhibitor to a substrate. Hydroxyethyl starch (HES) dilution enhances fibrinolysis by diminishing alpha2-antiplasmin-plasmin interactions. the Arg6Trp polymorphism may play a significant role in governing the long-term deposition/removal of intravascular fibrin. TAFIa, PAI-1 and alpha-antiplasmin: complementary roles in regulating lysis of thrombi and plasma clots. Alpha2-antiplasmin has an important role in acute pulmonary embolism. Multiple Lys residues within alpha 2-antiplasmin contribute, perhaps in a zipper-like fashion, to its binding to the in-tandem, multikringle array that configures the plasmin heavy chain. alpha2-antiplasmin induction inhibits E-cadherin processing mediated by the plasminogen activator/plasmin system, leading to suppression of progression of oral squamous cell carcinoma via upregulation of cell-cell adhesion

Alternate Names

alpha 2-Antiplasmin

Gene Symbol

SERPINF2

Additional Serpin F2/alpha 2-Antiplasmin Products

Product Documents for Human Serpin F2/alpha 2-Antiplasmin ELISA Kit (Colorimetric)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Human Serpin F2/alpha 2-Antiplasmin ELISA Kit (Colorimetric)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

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