TRANCE/TNFSF11/RANK L Antibody Pair [HRP]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-79357

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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Key Product Details

Assay Type

Sandwich ELISA

Assay Range

234.38-15000 pg/ml (example only; lot dependent)

Sensitivity

234.38 pg/ml (example only; lot dependent)

Reactivity

Human

View all TRANCE/TNFSF11/RANK L ELISA Kits »

Product Specifications

Description

Solid Phase sandwich ELISA for the quantitative determination of Human TRANCE/TNFSF11/RANK L.

Sample Volume Required

100 ul

Conjugate

HRP

Scientific Data Images for TRANCE/TNFSF11/RANK L Antibody Pair [HRP]

Sandwich ELISA: TRANCE/TNFSF11/RANK L Antibody Pair [HRP] [NBP2-79357] - This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.

Kit Contents for TRANCE/TNFSF11/RANK L Antibody Pair [HRP]

  • Rabbit Monoclonal Capture Antibody: (Catalog # NBP2-89958)
  • Rabbit Monoclonal Detection Antibody (HRP-conjugated): (Catalog # NBP2-89957)
  • Standard

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Storage of components varies. See protocol for specific instructions.

Background: TRANCE/TNFSF11/RANK L

TRANCE/OPGL/RANKL/ODF is a recently identified member of tumor necrosis factor family. TRANCE (TNF-related activation-induced cytokine receptor) or RANKL {receptor activator of NF-kB (RANK) ligand} has been implicated in interactions between T cells and dendritic cells (1-2). RANK ligand (RANKL/TRANCE) binds to RANK on dendritic cells, upregulates the expression of anti-apoptotic protein BcL-XL suggesting a role in dendritic cell survival (2). TRANCE/RANKL is also important in T and B-cell maturation (3). As OPGL/ODF (Osteoprotegerin Ligand/Osteoclast differentiation factor), the same protein can both activate mature osteoclasts and mediate osteoclastogenesis (4). OPGL/TRANCE deficient mice show severe osteoporesis and complete absence of osteoclasts as a result of lack of osteogenesis (3).

Long Name

TNF-related Activation-induced Cytokine

Alternate Names

CD254, ODF, OPGL, RANK L, RANKL, TNFSF11

Gene Symbol

TNFSF11

Additional TRANCE/TNFSF11/RANK L Products

Product Documents for TRANCE/TNFSF11/RANK L Antibody Pair [HRP]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for TRANCE/TNFSF11/RANK L Antibody Pair [HRP]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

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