IgG is a monomeric immunoglobulin, built of two heavy chains gamma and two light chains. Each molecule has two antigen binding sites. This is the most abundant immunoglobulin and is approximately equally distributed in blood and in tissue liquids, constituting 75% of serum immunoglobulins in humans. This is the only isotype that can pass through the human placenta, thereby providing protection to the fetus in its first weeks of life before its own immune system has developed. It can bind to many kinds of pathogens, for example viruses, bacteria, and fungi, and protects the body against them by complement activation (classic pathway), opsonization for phagocytosis and neutralisation of their toxins. There are 4 subclasses: IgG1 (66%), IgG2 (23%), IgG3 (7%) and IgG4 (4%).

Long Name

Immunoglobulin G

Alternate Names

Immunoglobulin G, ImmunoglobulinG

Gene Symbol

IGHG1

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Product Documents for Rabbit IgG Isotype Control [Janelia Fluor 646]

Product Datasheets

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COA

SDS

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Product Specific Notices for Rabbit IgG Isotype Control [Janelia Fluor 646]

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Isotype Controls are guaranteed for 1 year from date of receipt.

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Rabbit IgG Isotype Control [Janelia Fluor 646]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-24891JF646

Key Product Details

Species Reactivity

Applications

Label

Antibody Source

Concentration

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Product Specifications

Clonality

Host

Isotype

Applications for Rabbit IgG Isotype Control [Janelia Fluor 646]

Flow Cytometry

Immunocytochemistry/ Immunofluorescence

Immunohistochemistry

Immunohistochemistry-Paraffin

Formulation, Preparation, and Storage

Purification

Formulation

Preservative

Concentration

Shipping

Stability & Storage

Background: IgG