Human IgG Isotype Control

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-21949

Novus Biologicals, part of Bio-Techne
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NBP2-21949-0.25mg
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Key Product Details

Species Reactivity

Human

Label

Unconjugated

Antibody Source

Polyclonal Human IgG

Concentration

LYOPH mg/ml

View all IgG Isotype Controls »

Product Specifications

Clonality

Polyclonal

Host

Human

Isotype

IgG

Description

This Human IgG immunoglobulin is useful as an isotype control for Human IgG antibody. This antibody is purified from Human serum with protein A/G. Endotoxin level < 1.5 EU/mg.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Reconstitution

Reconstitute with PBS.

Formulation

Lyophilized from a 0.2 um filtered solution in PBS. 0.5mg and 0.25 mg sizes are provided in liquid form, PBS

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: IgG

IgG is a monomeric immunoglobulin, built of two heavy chains gamma and two light chains. Each molecule has two antigen binding sites. This is the most abundant immunoglobulin and is approximately equally distributed in blood and in tissue liquids, constituting 75% of serum immunoglobulins in humans. This is the only isotype that can pass through the human placenta, thereby providing protection to the fetus in its first weeks of life before its own immune system has developed. It can bind to many kinds of pathogens, for example viruses, bacteria, and fungi, and protects the body against them by complement activation (classic pathway), opsonization for phagocytosis and neutralisation of their toxins. There are 4 subclasses: IgG1 (66%), IgG2 (23%), IgG3 (7%) and IgG4 (4%).

Long Name

Immunoglobulin G

Alternate Names

Immunoglobulin G, ImmunoglobulinG

Gene Symbol

IGHG1

Additional IgG Products

Product Documents for Human IgG Isotype Control

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Human IgG Isotype Control

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Isotype Controls are guaranteed for 1 year from date of receipt.

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