AGTR-2 Antibody Blocking Peptide

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-77368PEP

Novus Biologicals, part of Bio-Techne
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Key Product Details

Source

Synthetic

Conjugate

Unconjugated

Applications

Antibody Competition

View all AGTR-2 Proteins and Enzymes »

Product Specifications

Description

A blocking peptide containing 16 amino acids near the center of human AGTR2.

Source: Synthetic

(Accession #: AAS45437)

Purity

N/A

Application Notes

This peptide is useful as a blocking peptide for NBP1-77368. For further blocking peptide related protocol, click here.

Protein / Peptide Type

Antibody Blocking Peptide

Formulation, Preparation and Storage

NBP1-77368PEP
Formulation PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin.
Preservative 0.02% Sodium Azide
Concentration 0.2 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -20C. Avoid freeze-thaw cycles.

Background: AGTR-2

Angiotensin II is a potent pressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors termed AT1 and AT2. AGTR2 belongs to a family 1 of G-protein coupled receptors. It is an intergral membrane protein. It plays a role in the central nervous system and cardiovascular functions that are mediated by the renin-angiotensin system. This receptor mediates programmed cell death (apoptosis). In adults, it is highly expressed in myometrium with lower levels in adrenal gland and fallopian tube. It is highly expressed in fetal kidney and intestine. The human AGTR2 gene is composed of three exons and spans at least 5 kb. Exons 1 and 2 encode for 5; untranslated mRNA sequence and exon 3 harbors the entire uninterrupted open reading frame.

Long Name

Angiostensin II Type 2 Receptor

Alternate Names

AGTR2, AT2, AT2R, MRX88

Gene Symbol

AGTR2

Additional AGTR-2 Products

Product Documents for AGTR-2 Antibody Blocking Peptide

Product Datasheets

Certificate of Analysis

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Product Specific Notices for AGTR-2 Antibody Blocking Peptide

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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