Amino Acid Sequence: MDVTIQHPWF KRTLGPFYPS RLFDQFFGEG LFEYDLLPFL SSTISPYYRQ SLFRTVLDSG ISEVRSDRDK FVIFLDVKHF SPEDLTVKVQ DDFVEIHGKH NERQDDHGYI SREFHRRYRL PSNVDQSALS CSLSADGMLT FCGPKIQTGL DATHAERAIP VSREEKPTSA PSS

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

19.9 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human AlphaA Crystallin/CRYAA Protein

SDS-Page: Recombinant Human AlphaA Crystallin/CRYAA Protein [NBC1-18351] -

SDS-Page: Recombinant Human AlphaA Crystallin/CRYAA Protein [NBC1-18351] - 3ug by SDS-PAGE under reducing condition and visualized by Coomassie blue stain.

Formulation, Preparation and Storage

NBC1-18351

Formulation	20 mM Tris-HCl buffer (pH 7.5), 50 mM NaCl, 1 mM EDTA.
Preservative	No Preservative
Concentration	1 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: AlphaA Crystallin/CRYAA

Alpha crystallins are composed of two gene products ; alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein(sHSP also known as the HSP20). They act as molecular chaperones and hold them in large soluble aggregates. These heterogeneous aggregates consist of 30-40 subunits; the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional function of alpha-crystallins are an autokinase activity and participation in the intracellular architecture. The expression of alpha-A is preferentially restricted to the lens cell.

Alternate Names

CRYA1, CRYAA, HSPB4

Gene Symbol

CRYAA

Additional AlphaA Crystallin/CRYAA Products

Product Documents for Recombinant Human AlphaA Crystallin/CRYAA Protein

Product Datasheets

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COA

Product Specific Notices for Recombinant Human AlphaA Crystallin/CRYAA Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

Citations
Reviews

Recombinant Human AlphaA Crystallin/CRYAA Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBC1-18351

Key Product Details

Source

Conjugate

Applications

View all AlphaA Crystallin/CRYAA Proteins and Enzymes »

Product Specifications

Description