Amino Acid Sequence: MDIAIHHPWI RRPFFPFHSP SRLFDQFFGE HLLESDLFPT STSLSPFYLR PPSFLRAPSW FDTGLSEMRL EKDRFSVNLD VKHFSPEELK VKVLGDVIEV HGKHEERQDE HGFISREFHR KYRIPADVDP LTITSSLSSD GVLTVNGPRK QVSGPERTIP ITREEKPAVT AAPKK

Purity

>95%, by SDS-PAGE

Predicted Molecular Mass

20.1 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Reviewed Applications

Read 1 review rated 5 using NBC1-18352 in the following applications:

In vivo study (1 Review)

Scientific Data Images for Recombinant Human AlphaB Crystallin/CRYAB Protein

SDS-PAGE: Recombinant Human AlphaB Crystallin/CRYAB Protein [NBC1-18352]

SDS-Page: Recombinant Human AlphaB Crystallin/CRYAB Protein [NBC1-18352] - 3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain

Formulation, Preparation and Storage

NBC1-18352

Formulation	20 mM Tris-HCl buffer (pH 7.5), 50 mM NaCl, 1 mM EDTA
Preservative	No Preservative
Concentration	1 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: AlphaB Crystallin/CRYAB

Alpha crystallins are composed of two gene products ; alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein(sHSP also known as the HSP20). They act as molecular chaperones and hold them in in large soluble aggregates. These heterogeneous aggregates consist of 30-40 subunits; the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional function of alpha-crystallins are an autokinase activity and participation in the intracellular architecture. Alpha-B is expressed widely in many tissues and organs and occurs in many neurological diseases.

Alternate Names

CRYA2, CRYAB, CTPP2, HSPB5

Gene Symbol

CRYAB

Additional AlphaB Crystallin/CRYAB Products

Product Documents for Recombinant Human AlphaB Crystallin/CRYAB Protein

Product Datasheets

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COA

Product Specific Notices for Recombinant Human AlphaB Crystallin/CRYAB Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

Citations
Reviews

Recombinant Human AlphaB Crystallin/CRYAB Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBC1-18352

Key Product Details

Source

Conjugate

Applications

View all AlphaB Crystallin/CRYAB Proteins and Enzymes »

Product Specifications

Description