APRIL/TNFSF13 Antibody Blocking Peptide

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76767PEP

Novus Biologicals, part of Bio-Techne
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NBP1-76767PEP
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Key Product Details

Source

Synthetic

Conjugate

Unconjugated

Applications

Antibody Competition

View all APRIL/TNFSF13 Proteins and Enzymes »

Product Specifications

Description

A blocking peptide containing 15 amino acids near the extracellular domain of human APRIL.

Source: Synthetic

(Accession #: NP_003799)

Purity

N/A

Application Notes

This peptide is useful as a blocking peptide for NBP1-76767. For further blocking peptide related protocol, click here.

Protein / Peptide Type

Antibody Blocking Peptide

Formulation, Preparation and Storage

NBP1-76767PEP
Formulation PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin.
Preservative 0.02% Sodium Azide
Concentration 0.2 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -20C. Avoid freeze-thaw cycles.

Background: APRIL/TNFSF13

TNFSF13 is a proliferation-inducing ligand (APRIL), also designated TNFSF13, is a Type II membrane protein that shares characteristics with other members of the tumor necrosis factor (TNF) cytokine family. APRIL is expressed in high levels in transformed cell lines and in human colon, thyroid, and lymphoid tumor tissues. APRIL is critically involved in the regulation of infections, inflammation, autoimmune diseases, and tissue homeostasis. APRIL is implicated in the regulation of tumor cell growth. The C-terminal extracellular domain has b jelly roll topography and is important in ligand trimerization. The binding of the ligand to its respective receptor induces oligomerization, initiating downstream signaling events. Intrinsic to oligomerization is the formation of the receptor binding site at the junction between neighboring subunits, creating a multivalent ligand.

Long Name

A Proliferation-inducing Ligand

Alternate Names

CD256, TALL2, TNFSF13, TRDL1, ZTNF2

Gene Symbol

TNFSF13

Additional APRIL/TNFSF13 Products

Product Documents for APRIL/TNFSF13 Antibody Blocking Peptide

Product Datasheets

Certificate of Analysis

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Product Specific Notices for APRIL/TNFSF13 Antibody Blocking Peptide

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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