Recombinant Human ARPP19 His Protein

Name: Recombinant Human ARPP19 His Protein
Brand: Novus Biologicals
SKU: NBP2-22727

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-22727

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Technical Data
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Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all ARPP19 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-112 of Human ARPP19

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSAEVPE AASAEEQKEM EDKVTSPEKA EEAKLKARYP HLGQKPGGSD FLRKRLQKGQ KYFDSGDYNM AKAKMKNKQL PTAAPDKTEV TGDHIPTPQD LPQRKPSLVA SKLAG

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

14.7 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human ARPP19 His Protein

SDS-PAGE: Recombinant Human ARPP19 His Protein [NBP2-22727]

SDS-Page: Recombinant Human ARPP19 Protein [NBP2-22727]

Formulation, Preparation and Storage

NBP2-22727

Formulation	20 mM Tris-HCl buffer (pH 8.0), 0.15 M NaCl, 10% glycerol
Preservative	No Preservative
Concentration	0.5 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ARPP19

cAMP-regulated phosphoprotein 19, also known as ARPP19, is protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-62 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase. This protein may indirectly enhance GAP-43 expression. Recombinant human ARPP19 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Alternate Names

ARPP-16, ARPP16cAMP-regulated phosphoprotein 19, ARPP-19FLJ41622, cAMP-regulated phosphoprotein, 19kDa, cyclic AMP phosphoprotein, 19 kD, ENSAL

Gene Symbol

ARPP19

Additional ARPP19 Products

Product Documents for Recombinant Human ARPP19 His Protein

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COA

Product Specific Notices for Recombinant Human ARPP19 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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