Recombinant Human ATPase Inhibitory Factor 1 His Protein

Name: Recombinant Human ATPase Inhibitory Factor 1 His Protein
Brand: Novus Biologicals
SKU: NBP1-98902

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-98902

Submit a review

Product Datasheet / COA

100% Guarantee

Technical Data
Citations & Reviews

Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all ATPase Inhibitory Factor 1 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 26-106 of Human ATPase Inhibitory Factor 1

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMGSDQS ENVDRGAGSI REAGGAFGKR EQAEEERYFR AQSREQLAAL KKHHEEEIVH HKKEIERLQK EIERHKQKIK MLKHDD

Purity

>95%, by SDS-PAGE

Predicted Molecular Mass

12.2 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human ATPase Inhibitory Factor 1 His Protein

SDS-PAGE: Recombinant Human ATPase Inhibitory Factor 1 His Protein [NBP1-98902]

SDS-Page: Recombinant Human ATPase Inhibitory Factor 1 His Protein [NBP1-98902] - 3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.

Formulation, Preparation and Storage

NBP1-98902

Formulation	20 mM Tris-HCl buffer (pH 8.0), 0.2 M NaCl, 50% glycerol
Preservative	No Preservative
Concentration	1 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ATPase Inhibitory Factor 1

ATPase inhibitory factor 1, also known as ATPIF1, binds to the C-terminal region of a beta subunit of the F1-ATPase at low pH values and, via interference of the beta and gamma subunit interaction, ATPIF1 regulates the activity of the F1 (the hydrophilic catalytic core), F0 (the membrane embedded protein channel) ATPase. The overexpression of ATPIF1 in several human carcinomas further supports its participation in oncogenesis and provides insight into the altered metabolism of cancer cells, which includes the reprogramming of energetic metabolism toward glycolysis. Recombinant human ATPIF1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Alternate Names

ATP synthase inhibitor protein, ATPase inhibitor protein, ATPase inhibitor, mitochondrial, ATPase inhibitory factor 1, ATPIIF(1), ATPIP, IF1, Inhibitor of F(1)F(o)-ATPase, IP, MGC1167, MGC8898

Gene Symbol

ATP5IF1

Additional ATPase Inhibitory Factor 1 Products

Product Documents for Recombinant Human ATPase Inhibitory Factor 1 His Protein

Product Datasheets

Download Product Datasheets

COA

Product Specific Notices for Recombinant Human ATPase Inhibitory Factor 1 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

Citations
Reviews