BACE-2 Antibody Blocking Peptide

Name: BACE-2 Antibody Blocking Peptide
Brand: Novus Biologicals
SKU: NBP1-77308PEP

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-77308PEP

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Technical Data
Citations & Reviews

Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

Synthetic

Conjugate

Unconjugated

Applications

Antibody Competition

View all BACE-2 Proteins and Enzymes »

Product Specifications

Description

A blocking peptide containing 16 amino acids near the carboxy terminus of human BACE2.

Source: Synthetic

(Accession #: AAF17078)

Purity

N/A

Application Notes

This peptide is useful as a blocking peptide for NBP1-77308. For further blocking peptide related protocol, click here.

Protein / Peptide Type

Antibody Blocking Peptide

Scientific Data Images for BACE-2 Antibody Blocking Peptide

Western Blot: BACE-2 Antibody Blocking Peptide [NBP1-77308PEP]

Western Blot: BACE2 Peptide [NBP1-77308PEP] - blocks the antibody activity completely in Western blot by incubating the peptide with equal volume of antibody for 30 min at 37C

Formulation, Preparation and Storage

NBP1-77308PEP

Formulation	PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin.
Preservative	0.02% Sodium Azide
Concentration	0.2 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at -20C. Avoid freeze-thaw cycles.

Background: BACE-2

BACE2 (Memapsin 1) is a membrane-bound aspartic protease that is highly homologous with BACE1 (Memapsin 2). While BACE1 processes the amyloid precursor protein (APP) at a key step in generating the beta-amyloid peptide and presumably causes Alzheimer's disease (AD), BACE2 has not been demonstrated to be directly involved in APP processing, and its physiological functions remain to be determined. In vivo, BACE2 is expressed as a precursor protein containing pre-, pro-, protease, transmembrane, and cytosolic domains/peptides.

Long Name

beta-site Ayloid Precursor Protein Cleaving Enzyme 2

Alternate Names

BACE2

Gene Symbol