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Recombinant Human BAFFR/TNFRSF13C Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-34879

Novus Biologicals, part of Bio-Techne
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NBP2-34879-100ug
NBP2-34879-10ug
NBP2-34879-1mg
NBP2-34879-500ug

Key Product Details

Source

E. coli

Accession #

Conjugate

Unconjugated

Applications

Bioactivity, SDS-PAGE

Product Specifications

Description

A single non-glycosylated polypeptide chain containing 76 amino acids corresponding to BAFFR/TNFRSF13C Source: E. coli

Uniprot ID: Q96RJ3

Amino Acid Sequence: MRRGPRSLRG RDAPAPTPCV PAECFDLLVR HCVACGLLRT PRPKPAGASS PAPRTALQPQ ESVGAGAGEA ALPLPG

Purity

>95%, by reducing SDS-PAGE

Endotoxin Level

Less than 1 EU/ug of BAFFR/TNFRSF13C as determined by LAL method.

Predicted Molecular Mass

7.8 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Activity

BAFF Receptor protein is fully biologically active when compared to standard. The ED50 as determined by its ability to block BAFF induced mouse splenocyte survival is 1.0-5.0 ug/ml in the presence of 1.0 ug/ml of rHuBAFF.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human BAFFR/TNFRSF13C Protein

Recombinant Human BAFFR/TNFRSF13C Protein

SDS-Page: Recombinant Human BAFFR/TNFRSF13C Protein [NBP2-34879]

SDS-Page: Recombinant Human BAFFR/TNFRSF13C Protein [NBP2-34879]

Formulation, Preparation and Storage

NBP2-34879
Formulation Lyophilized from a 0.2 um filtered concentrated solution in 20 mM PB, pH 8.0, 500 mM NaCl.
Preservative No Preservative
Concentration Lyoph
Reconstitution Recommended to centrifuge prior to opening. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/mL. Apportion stock solutions into working aliquots and store at
Format Carrier-Free
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -20 to -70C as supplied. After reconstitution, store at 2 to 8C for 1 month and at -20 to -70C for long term storage. Avoid repeated freeze-thaw cycles.

Background: BAFFR/TNFRSF13C

B Cell Activating Factor Receptor (BAFF-R), also named tumor necrosis factor receptor superfamily member 13C, is a member of the TNFR superfamily. It is highly expressed in spleen, lymph node, and resting B cells and to some extent in activated B cells, resting CD4+ cells and peripheral blood leukocytes. BAFF receptor is a type III transmembrane protein containing a single extracellular phenylalanine-rich domain and binds with high specificity to BAFF (TNFSF13B). It enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. BAFF receptor/BAFF signaling plays a critical role in B cell survival and maturation.

Long Name

B cell Activating Factor Receptor

Alternate Names

BAFF R, BR3, CD268, TNFRSF13C, BAFF Receptor/TNFRSF13C

Gene Symbol

TNFRSF13C

UniProt

Additional BAFFR/TNFRSF13C Products

Product Documents for Recombinant Human BAFFR/TNFRSF13C Protein

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Recombinant Human BAFFR/TNFRSF13C Protein

This lyophilized preparation is stable for 12 months from date of receipt at -20 to -70 degrees C, preferably desiccated. Upon reconstitution, the preparation can be stored for 1 month at 2-8 degrees C under sterile conditions, and for 3 months at -20 degrees C to -70 degrees C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Stock solutions should be aliquoted and stored at < -20 degrees C. Further dilutions should be made in appropriate buffered solutions

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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