Bcl-2 related protein A1 Antibody Blocking Peptide

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76715PEP

Novus Biologicals, part of Bio-Techne
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NBP1-76715PEP
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Key Product Details

Source

Synthetic

Conjugate

Unconjugated

Applications

Antibody Competition

View all Bcl-2 related protein A1 Proteins and Enzymes »

Product Specifications

Description

A blocking peptide containing 14 amino acids near the carboxy terminus of human Bcl-2 related protein A1.

Source: Synthetic

(Accession #: NP_004040)

Purity

N/A

Application Notes

This peptide is useful as a blocking peptide for NBP1-76715. For further blocking peptide related protocol, click here.

Protein / Peptide Type

Antibody Blocking Peptide

Formulation, Preparation and Storage

NBP1-76715PEP
Formulation PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin.
Preservative 0.02% Sodium Azide
Concentration 0.2 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -20C. Avoid freeze-thaw cycles.

Background: Bcl-2 related protein A1

Bcl-2 related protein A1; also known as Bcl2A1 and Bfl1, is an anti-apoptotic Bcl-2 family member preferentially expressed in hematopoietic and endothelial cells (1). Bfl1 is involved in a variety of cellular activities such as embryonic development, homeostatis and tumorigenesis. Expression of Bfl1 is stimulated by NF-kB in response to inflammatory stimuli and is up-regulated by TNF-alpha, IL1-beta, IGF1, GMC-SF, CD40 and phorbol ester (2-3). Blf1 has also been shown to reduce the release of pro-apoptotic cytochrome c from the mitochondria, block caspase activation and suppress apoptosis induced by p53 (4-5).

Alternate Names

BCL2A1, Bcl2L5, Bfl-1, GRS

Gene Symbol

BCL2A1

Additional Bcl-2 related protein A1 Products

Product Documents for Bcl-2 related protein A1 Antibody Blocking Peptide

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Bcl-2 related protein A1 Antibody Blocking Peptide

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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