Recombinant Human CA11 His Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-22731

Novus Biologicals, part of Bio-Techne
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Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all CA11 Proteins and Enzymes »

Product Specifications

Description

A denatured recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 24-328 of Human CA11

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MHIGPAPDPE DWWSYKDNLQ GNFVPGPPFW GLVNAAWSLC AVGKRQSPVD VELKRVLYDP FLPPLRLSTG GEKLRGTLYN TGRHVSFLPA PRPVVNVSGG PLLYSHRLSE LRLLFGARDG AGSEHQINHQ GFSAEVQLIH FNQELYGNFS AASRGPNGLA ILSLFVNVAS TSNPFLSRLL NRDTITRISY KNDAYFLQDL SLELLFPESF GFITYQGSLS TPPCSETVTW ILIDRALNIT SLQMHSLRLL SQNPPSQIFQ SLSGNSRPLQ PLAHRALRGN RDPRHPERRC RGPNYRLHVD GVPHGR

Purity

>85%, by SDS-PAGE

Predicted Molecular Mass

36.3 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Application Notes

Denatured protein is most likely not the best option for functional studies. It is better suited for Western Blot (WB) or imaging assays.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human CA11 His Protein

SDS-PAGE: Recombinant Human CA11 His Protein [NBP2-22731]

SDS-PAGE: Recombinant Human CA11 His Protein [NBP2-22731]

SDS-Page: CA11 Protein [NBP2-22731]

Formulation, Preparation and Storage

NBP2-22731
Formulation 20 mM Tris-HCl buffer (pH 8.0), 0.4M UREA, 10% glycerol
Preservative No Preservative
Concentration 1 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CA11

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA11 is likely a secreted protein, however, radical changes at active site residues completely conserved in CA isozymes with catalytic activity, make it unlikely that it has carbonic anhydrase activity. It shares properties in common with two other acatalytic CA isoforms, CA VIII and CA X. CA11 is most abundantly expressed in brain, and may play a general role in the central nervous system. Recombinant human CA11 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Long Name

Carbonic anhydrase-related protein 11

Alternate Names

CA-RP II, CA-RP XI, CA-XI, CARP XI, CARP-2, CARP2, UNQ211/PRO237

Gene Symbol

CA11

Additional CA11 Products

Product Documents for Recombinant Human CA11 His Protein

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Recombinant Human CA11 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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