Recombinant Human CDK2AP1 His Protein

Name: Recombinant Human CDK2AP1 His Protein
Brand: Novus Biologicals
SKU: NBP1-40398

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-40398

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Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all CDK2AP1 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-115 of Human CDK2AP1

Source: E.coli

Amino Acid Sequence: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMSY KPNLAAHMPA AALNAAGSVH SPSTSMATSS QYRQLLSDYG PPSLGYTQGT GNSQVPQSKY AELLAIIEEL GKEIRPTYAG SKSAMERLKR GIIHARGLVR ECLAETERNA RS

Purity

>95%, by SDS-PAGE

Predicted Molecular Mass

16.6 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human CDK2AP1 His Protein

SDS-PAGE: Recombinant Human CDK2AP1 His Protein [NBP1-40398]

SDS-Page: Recombinant Human CDK2AP1 Protein [NBP1-40398] - 15 % SDS-PAGE (3ug)

Formulation, Preparation and Storage

NBP1-40398

Formulation	20 mM Tris-HCl buffer (pH8.0), 50% glycerol, 2 mM DTT
Preservative	No Preservative
Concentration	0.25 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CDK2AP1

CDK2AP1 is a specific CDK2-associated protein, which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. Also, interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggested the regulatory role in DNA replication during S phase of the cell cycle. A similar gene in hamster was isolated from, and functions as a growth suppressor of normal keratinocytes. Recombinant CDK2AP1 protein was expressed in E.coli and purified by using conventional chromatography techniques.

Alternate Names

CDK2-associated protein 1cyclin-dependent kinase 2-associated protein 1, CDKAP1, cyclin-dependent kinase 2 associated protein 1, Deleted in oral cancer 1, Deleted in oral cancer-1, DOC-1, DOC1Putative oral cancer suppressor, DORC1, p12DOC-1, ST19

Gene Symbol

CDK2AP1

Additional CDK2AP1 Products

Product Documents for Recombinant Human CDK2AP1 His Protein

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COA

Product Specific Notices for Recombinant Human CDK2AP1 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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