Recombinant Human CKS1 His Protein

Name: Recombinant Human CKS1 His Protein
Brand: Novus Biologicals
SKU: NBP2-51527

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-51527

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Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all CKS1 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-79 of Human CKS1

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSHKQIY YSDKYDDEEF EYRHVMLPKD IAKLVPKTHL MSESEWRNLG VQQSQGWVHY MIHEPEPHIL LFRRPLPKKP KK

Purity

>95%, by SDS-PAGE

Predicted Molecular Mass

12 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human CKS1 His Protein

SDS-PAGE: Recombinant Human CKS1 His Protein [NBP2-51527]

SDS-Page: Recombinant Human CKS1 Protein [NBP2-51527] - 15% SDS Page (3 ug)

Formulation, Preparation and Storage

NBP2-51527

Formulation	20 mM Tris-HCl buffer (pH 8.0), 0.15 M NaCl, 20% glycerol, 1 mM DTT
Preservative	No Preservative
Concentration	1 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CKS1

CKS1B (Cyclin-dependent kinases regulatory subunit 1) is a 79 amino acid protein that binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. Depleting CKS1B in breast cancer cells has been shown to slow cell cycle progression and regulation of CKS1B may provide a potential cancer treatment option. Besides breast cancer, CKS1B plays a role in multiple myeloma, adenocarcinoma, mantle cell lymphoma , oral squamous cell carcinoma, squamous cell carcinoma, cholesteatoma, paracoccidioidomycosis, intrahepatic cholangiocarcinoma, hepatoblastoma, hepatocellular carcinoma, non-small cell lung carcinoma, gallbladder carcinoma, basal cell carcinoma, endometrial carcinoma, renal cell carcinoma and thyroid carcinoma.

Alternate Names

CDC28 protein kinase 1, CDC28 protein kinase 1B, CDC28 protein kinase regulatory subunit 1B, cell division control protein CKS1, CKS-1, CKS1CDC2-associated protein CKS1, ckshs1, cyclin-dependent kinases regulatory subunit 1, NB4 apoptosis/differentiation related protein, PNAS-143, PNAS-16, PNAS-18

Gene Symbol

CKS1B

Additional CKS1 Products

Product Documents for Recombinant Human CKS1 His Protein

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COA

Product Specific Notices for Recombinant Human CKS1 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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