Recombinant Human CMP kinase His Protein

Name: Recombinant Human CMP kinase His Protein
Brand: Novus Biologicals
SKU: NBP1-51052

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-51052

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Product Specifications
Scientific Data
Preparation & Storage
Background
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Specific Notices

Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

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Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-228 of Human CMP kinase

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MLSRCRSGLL HVLGLSFLLQ TRRPILLCSP RLMKPLVVFV LGGPGAGKGT QCARIVEKYG YTHLSAGELL RDERKNPDSQ YGELIEKYIK EGKIVPVEIT ISLLKREMDQ TMAANAQKNK FLIDGFPRNQ DNLQGWNKTM DGKADVSFVL FFDCNNEICI ERCLERGKSS GRSDDNRESL EKRIQTYLQS TKPIIDLYEE MGKVKKIDAS KSVDEVFDEV VQIFDKEG

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

28 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human CMP kinase His Protein

SDS-PAGE: Recombinant Human CMP kinase His Protein [NBP1-51052]

SDS-Page: Recombinant Human CMP kinase Protein [NBP1-51052] - 15 % SDS-PAGE (3ug)

Formulation, Preparation and Storage

NBP1-51052

Formulation	20 mM Tris-HCl buffer (pH8.0), 20% glycerol, 1 mM DTT, 100 mM NaCl
Preservative	No Preservative
Concentration	1 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CMP kinase

CMPK1, also known as UMP-CMP kinase and deoxycytidylate kinase, is an enzyme that catalyzes the phosphoryl transfer from ATP to UMP, CMP and dCMP. This enzymatic reaction leads to the formation of ADP and the corresponding nucleoside diphosphate, which are required for cellular nucleic acid synthesis. It also plays an important role in the activation of pyrimidine analogs, which are clinically useful anti-cancer and anti-viral drugs. Recombinant human CMPK1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Alternate Names

CMKEC 2.7.4.14, CMPKUMKUMP-CMP kinase, cytidine monophosphate (UMP-CMP) kinase 1, cytosolic, Cytidine monophosphate kinase, Cytidylate kinaseUMP/CMP kinase, Deoxycytidylate kinase, EC 2.7.4, UMP/CMPK, UMP-CMPK, UMPKUCK, Uridine monophosphate kinase, Uridine monophosphate/cytidine monophosphate kinase

Gene Symbol

CMPK1

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COA

Product Specific Notices for Recombinant Human CMP kinase His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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