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Recombinant Mouse CXCL11/I-TAC Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-61348

Novus Biologicals, part of Bio-Techne
Catalog #
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NBP2-61348-1000ug
NBP2-61348-100ug
NBP2-61348-500ug
NBP2-61348-5ug

Key Product Details

Source

E. coli

Conjugate

Unconjugated

Applications

Bioactivity

Product Specifications

Description

A single non-glycosylated polypeptide chain containing 79 amino acids corresponding to CXCL11/I-TAC Source: E. coli

Uniprot ID: Q9JHH5

Amino Acid Sequence: FLMFKQGRCL CIGPGMKAVK MAEIEKASVI YPSNGCDKVE VIVTMKAHKR QRCLDPRSKQ ARLIMQAIEK KNFLRRQNM

Purity

>98%, by SDS-PAGE and HPLC

Endotoxin Level

Less than 1 EU/ug of CXCL11/I-TAC as determined by LAL method.

Predicted Molecular Mass

9.1 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Activity

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using murine CXCR3 transfected 293 cells is in a concentration of 10-100 ng/ml.

Protein / Peptide Type

Recombinant Protein

Formulation, Preparation and Storage

NBP2-61348
Formulation Lyophilized from a 0.2 um filtered concentrated solution in 10 mM Sodium Citrate, pH 4.0, with 600 mM NaCl.
Preservative No Preservative
Concentration Lyoph
Reconstitution Recommended to centrifuge prior to opening. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/mL. Apportion stock solutions into working aliquots and store at
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -20 to -70C as supplied. After reconstitution, store at 2 to 8C for 1 month and at -20 to -70C for long term storage. Avoid repeated freeze-thaw cycles.

Background: CXCL11/I-TAC

Small inducible cytokine B11 precursor; small inducible cytokine subfamily B (Cys-X-Cys), member 9B; small inducible cytokine subfamily B (Cys-X-Cys), member 11. This protein is a CXC member of the chemokine superfamily. It induces a chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3. The gene encoding this protein contains 4 exons and at least three polyadenylation signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of this gene.

Alternate Names

beta-R1, H174, I-TAC, ITAC, SCYB9B

Gene Symbol

CXCL11

Additional CXCL11/I-TAC Products

Product Documents for Recombinant Mouse CXCL11/I-TAC Protein

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Recombinant Mouse CXCL11/I-TAC Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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