CXCR6 Antibody Blocking Peptide

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76871PEP

Novus Biologicals, part of Bio-Techne
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Key Product Details

Source

Synthetic

Conjugate

Unconjugated

Applications

Antibody Competition

View all CXCR6 Proteins and Enzymes »

Product Specifications

Description

A blocking peptide containing 15 amino amino terminus of human Bonzo.

Source: Synthetic

(Accession #: AAB64221)

Purity

N/A

Application Notes

This peptide is useful as a blocking peptide for NBP1-76871. For further blocking peptide related protocol, click here.

Protein / Peptide Type

Antibody Blocking Peptide

Scientific Data Images for CXCR6 Antibody Blocking Peptide

Western Blot: CXCR6 Antibody Blocking Peptide [NBP1-76871PEP]

Western Blot: CXCR6 Antibody Blocking Peptide [NBP1-76871PEP]

Western Blot: CXCR6 Peptide [NBP1-76871PEP] - Incubating the peptide with equal volume of antibody for 30 min at 37C usually completely blocks the antibody activity in Western blotting.

Formulation, Preparation and Storage

NBP1-76871PEP
Formulation PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin.
Preservative 0.02% Sodium Azide
Concentration 0.2 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -20C. Avoid freeze-thaw cycles.

Background: CXCR6

Coreceptor usage of primary human immunodeficiency virus type 1 (HIV-1) isolates varies according to biological phenotype. The chemokine receptors CCR5 and CXCR4 are the major coreceptors that, together with CD4, govern HIV-1 entry into cells. Some HIV-1, HIV-2, and SIV isolates of different genetic subtypes and biological phenotypes use other chemokine receptors, such as CXCR6, a T-lymphocyte-expressed seven-transmembrane domain receptor that mediates fusion, entry, and trafficking of tumor-infiltrating lymphocytes. CXCR6 has been identified in human blood (T-lymphocytes, activated peripheral blood lymphocytes, monocyte-derived dendritic cells, primitive cord blood cells), placental trophoblasts, T-lymphocytes and dendritic cells in the skin, lymphoid tissues, and in fetal brain astrocytes. ESTs have been isolated from human normal placenta, liver/spleen, and pregnant uterus libraries, and human cancer kidney and uterus libraries.

Alternate Names

Bonzo, CD186, CXCR6, STRL33

Gene Symbol

CXCR6

Additional CXCR6 Products

Product Documents for CXCR6 Antibody Blocking Peptide

Product Datasheets

Certificate of Analysis

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Product Specific Notices for CXCR6 Antibody Blocking Peptide

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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