Recombinant Human D4-GDI/RhoGDI2 His Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-99054

Novus Biologicals, part of Bio-Techne
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NBP1-99054-10ug
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Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all D4-GDI/RhoGDI2 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a His-tag and corresponding to the amino acids 1-201 of Human D4-GDI/RhoGDI2

Source: E.coli

Amino Acid Sequence: MSPILGYWKI KGLVQPTRLL LEYLEEKYEE HLYERDEGDK WRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD LVPRGSHMTE KAPEPHVEED DDDELDSKLN YKPPPQKSLK ELQEMDKDDE SLIKYKKTLL GDGPVVTDPK APNVVVTRLT LVCESAPGPI TMDLTGDLEA LKKETIVLKE GSEYRVKIHF KVNRDIVSGL KYVQHTYRTG VKVDKATFMV GSYGPRPEEY EFLTPVEEAP KGMLARGTYH NKSFFTDDDK QDHLSWEWNL SIKKEWTE

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

49.4 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human D4-GDI/RhoGDI2 His Protein

SDS-PAGE: Recombinant Human D4-GDI/RhoGDI2 His Protein [NBP1-99054]

SDS-PAGE: Recombinant Human D4-GDI/RhoGDI2 His Protein [NBP1-99054]

SDS-Page: Recombinant Human D4-GDI/RhoGDI2 Protein [NBP1-99054] - 15% SDS-PAGE (3ug)
SDS-PAGE: Recombinant Human D4-GDI/RhoGDI2 His Protein [NBP1-99054]

SDS-PAGE: Recombinant Human D4-GDI/RhoGDI2 His Protein [NBP1-99054]

SDS-Page: Recombinant Human D4-GDI/RhoGDI2 Protein [NBP1-99054] - 15% SDS-PAGE (3ug)

Formulation, Preparation and Storage

NBP1-99054
Formulation PBS (pH 7.4), 10% glycerol
Preservative No Preservative
Concentration 1 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: D4-GDI/RhoGDI2

Members of the Rho (or ARH) protein family and other Ras-related small GTP-binding proteins are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases. Recombinant human ARHGDIB protein, fused to GST-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Alternate Names

ARHGDIB Rho GDP dissociation inhibitor (GDI) beta, D4, GDIA2, GDID4, LYGDI, Ly-GDI, RAP1GN1, RhoGDI2

Gene Symbol

ARHGDIB

Additional D4-GDI/RhoGDI2 Products

Product Documents for Recombinant Human D4-GDI/RhoGDI2 His Protein

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Recombinant Human D4-GDI/RhoGDI2 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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