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Recombinant Human Destrin His Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-98933

Novus Biologicals, part of Bio-Techne
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NBP1-98933-0.5mg
NBP1-98933-100ug

Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

Product Specifications

Description

A recombinant protein with a C-Terminal His-tag and corresponding to the amino acids 1-165 of Human Destrin

Source: E.coli

Amino Acid Sequence: MASGVQVADE VCRIFYDMKV RKCSTPEEIK KRKKAVIFCL SADKKCIIVE EGKEILVGDV GVTITDPFKH FVGMLPEKDC RYALYDASFE TKESRKEELM FFLWAPELAP LKSKMIYASS KDAIKKKFQG IKHECQANGP EDLNRACIAE KLGGSLIVAF EGCPVLEHHH HHH

Purity

>95%, by SDS-PAGE

Predicted Molecular Mass

19.5 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human Destrin His Protein

SDS-PAGE: Recombinant Human Destrin His Protein [NBP1-98933]

SDS-PAGE: Recombinant Human Destrin His Protein [NBP1-98933]

SDS-Page: Recombinant Human Destrin Protein [NBP1-98933] - 15% SDS-PAGE (3ug)

Formulation, Preparation and Storage

NBP1-98933
Formulation 20 mM Tris-HCl buffer (pH 8.0), 0.1 M NaCl, 10% glycerol, 1 mM DTT
Preservative No Preservative
Concentration 0.5 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Destrin

Destrin (actin depolymerizing factor), also known as DSTN, is a member of the ADF/Cofilin/destrin superfamily that has the ability to rapidly depolymerize F-Actin in a stoichiometric manner. DSTN is a small phosphoinositide-sensitive actin-binding protein capable of depolymerizing actin-filaments in vitro. It is found in various epithelial and endothelial cells but is practically absent from adult mouse heart and skeletal muscle cells. DSTN shares 71% sequence homology with Cofilin, however the two proteins differ in their interaction with Actin. Recombinant human DSTN protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Alternate Names

ACTDPdestrin, Actin-depolymerizing factor, ADFbA462D18.2 (destrin (actin depolymerizing factor ADF) (ACTDP)), bA462D18.2, destrin (actin depolymerizing factor), DSN

Gene Symbol

DSTN

Additional Destrin Products

Product Documents for Recombinant Human Destrin His Protein

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Recombinant Human Destrin His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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