Recombinant Human Dfna5 GST (N-Term) Protein

Name: Recombinant Human Dfna5 GST (N-Term) Protein
Brand: Novus Biologicals
SKU: H00001687-Q01

Novus Biologicals, part of Bio-Techne | Catalog # H00001687-Q01

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Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

Wheat germ

Tag

GST (N-Term)

Conjugate

Unconjugated

Applications

ELISA, Affinity Purification, Microarray, SDS-PAGE, Western Blot

View all Dfna5 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-terminal GST tag corresponding to the amino acid sequence 111-200 of Human Dfna5 deafness

Source: Wheat Germ (in vitro)

Amino Acid Sequence: SQSSFGTLRKQEVDLQQLIRDSAERTINLRNPVLQQVLEGRNEVLCVLTQKITTMQKCVISEHMQVEEKCGGIVGIQTKTVQVSATEDGN

Purity

>80% by SDS-PAGE and Coomassie blue staining

Predicted Molecular Mass

35.64 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Activity

This protein was produced in an in vitro wheat germ expression system that should preserve correct conformational folding that is necessary for biological function. While it is possible that this protein could display some level of activity, the functionality of this protein has not been explicitly measured or validated.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human Dfna5 GST (N-Term) Protein

SDS-PAGE: Recombinant Human Dfna5 GST (N-Term) Protein [H00001687-Q01]

SDS-Page: Recombinant Human, Dfna5 GST (N-Term) Protein [H00001687-Q01] - 12.5% SDS-PAGE Stained with Coomassie Blue.

Formulation, Preparation and Storage

H00001687-Q01

Preparation Method	in vitro wheat germ expression system
Formulation	50 mM Tris-HCI, 10 mM reduced Glutathione, pH 8.0 in the elution buffer.
Preservative	No Preservative
Concentration	Please see the vial label for concentration. If unlisted please contact technical services.
Shipping	The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at -80C. Avoid freeze-thaw cycles.

Background: Dfna5

Hearing impairment is a heterogeneous condition with over 40 loci described. The protein encoded by this gene is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq]

Alternate Names

deafness, autosomal dominant 5, DFNA5, deafness associated tumor suppressor, gasdermin-E, ICERE1, ICERE-1, Inversely correlated with estrogen receptor expression 1, nonsyndromic hearing impairment protein, non-syndromic hearing impairment protein 5

Gene Symbol

GSDME

Additional Dfna5 Products

Product Documents for Recombinant Human Dfna5 GST (N-Term) Protein

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COA

SDS

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Product Specific Notices for Recombinant Human Dfna5 GST (N-Term) Protein

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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