Recombinant Human GIP His Protein

Name: Recombinant Human GIP His Protein
Brand: Novus Biologicals
SKU: NBP2-23070

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-23070

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Technical Data
Citations & Reviews

Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all GIP Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 22-153 of Human His-tag GIP

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSEKKEGHF SALPSLPVGS HAKVSSPQPR GPRYAEGTFI SDYSIAMDKI HQQDFVNWLL AQKGKKNDWK HNITQREARA LELAGQANRK EEEAVEPQSS PAKNPSDEDL LRDLLIQELL ACLLDQTNLC RLRSR

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

17.3 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human GIP His Protein

SDS-PAGE: Recombinant Human GIP His Protein [NBP2-23070]

SDS-Page: Recombinant Human GIP Protein [NBP2-23070]

Formulation, Preparation and Storage

NBP2-23070

Formulation	20 mM Tris-HCl buffer (pH8.0), 50% glycerol, 0.1 M NaCl, 2 mM DTT
Preservative	No Preservative
Concentration	0.25 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GIP

GIP, also known as glucose-dependent insulinotropic polypeptide, is an important insulin-releasing hormone of the enteroinsular axis that has a functional profile of possible therapeutic value for type 2 diabetes. This protein is an important incretin hormone released into the circulation from endocrine K-cells of the duodenum and jejunum after ingestion of food1. It was evaluated for their ability to elevate cellular cAMP production and stimulate insulin secretion. It also promotes plasma triglyceride clearance in response to oral fat loading. In liver, GIP has been shown to enhance insulin-dependent inhibition of glycogenolysis. Recombinant human GIP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Long Name

Gastric Inhibitory Polypeptide

Alternate Names

Glucose-dependent Insulinotropic Polypeptide, Incretin

Gene Symbol

GIP

Additional GIP Products

Product Documents for Recombinant Human GIP His Protein

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COA

Product Specific Notices for Recombinant Human GIP His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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