Recombinant Human Glutaredoxin 3/GLRX3 His Protein

Name: Recombinant Human Glutaredoxin 3/GLRX3 His Protein
Brand: Novus Biologicals
SKU: NBP1-44478

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-44478

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Product Specifications
Scientific Data
Preparation & Storage
Background
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Specific Notices

Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all Glutaredoxin 3/GLRX3 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-335 of Human TXNL2

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MAAGAAEAAV AAVEEVGSAG QFEELLRLKA KSLLVVHFWA PWAPQCAQMN EVMAELAKEL PQVSFVKLEA EGVPEVSEKY EISSVPTFLF FKNSQKIDRL DGAHAPELTK KVQRHASSGS FLPSANEHLK EDLNLRLKKL THAAPCMLFM KGTPQEPRCG FSKQMVEILH KHNIQFSSFD IFSDEEVRQG LKAYSSWPTY PQLYVSGELI GGLDIIKELE ASEELDTICP KAPKLEERLK VLTNKASVML FMKGNKQEAK CGFSKQILEI LNSTGVEYET FDILEDEEVR QGLKAYSNWP TYPQLYVKGE LVGGLDIVKE LKENGELLPI LRGEN

Purity

>95%, by SDS-PAGE

Predicted Molecular Mass

39.6 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human Glutaredoxin 3/GLRX3 His Protein

SDS-PAGE: Recombinant Human Glutaredoxin 3/GLRX3 His Protein [NBP1-44478]

SDS-Page: Recombinant Human Glutaredoxin 3/GLRX3 Protein [NBP1-44478] - Glutaredoxin-3, 39.6kDa (355aa) with a purity of 95% by SDS - PAGE

Formulation, Preparation and Storage

NBP1-44478

Formulation	20 mM Tris-HCl buffer (pH8.0), 10% glycerol, 1 mM DTT
Preservative	No Preservative
Concentration	0.5 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Glutaredoxin 3/GLRX3

Glutaredoxin(GRX), also known as thioltransferase, is member of the thiol-disulfide oxidoreductase family. Glutraredoxin catalyzes the reversible reduction of protein-glutathionyl mixed disulfides to free sulfhydryl groups though a monothiol mechanism. Glutaredoxin-3 (Grx3/PICOT) is an essential protein involved in the regulation of signal transduction, for instance during immune cell activation and development of cardiac hypertrophy, presumably in response to redox signals. And it has been shown to interact with PRKCQ. Recombinant human Glutaredoxin-3, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Alternate Names

GLRX3, GLRX4, GRX3, GRX4, PICOT, TXNL2

Gene Symbol

GLRX3

Additional Glutaredoxin 3/GLRX3 Products

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COA

Product Specific Notices for Recombinant Human Glutaredoxin 3/GLRX3 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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