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GNPTG Recombinant Protein Antigen

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-88443PEP

Novus Biologicals, part of Bio-Techne
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NBP1-88443PEP

Key Product Details

Source

E. coli

Tag

N-terminal His6ABP (ABP = Albumin Binding Protein derived from Streptococcal Protein G)

Conjugate

Unconjugated

Applications

Antibody Competition

Product Specifications

Description

A recombinant protein antigen with a N-terminal His6-ABP tag corresponding to human GNPTG.

Source: E. coli

Amino Acid Sequence: PHALLVYPTLPEALQRQWDQVEQDLADELITPQGHEKLLRTLFEDAGYLKTPEENEPTQLEGGPDSLGFETLENCRKAHKELSKEIKRLKGLLTQHGIPYTRPTETSNLEHLG

Fusion Tag: N-terminal His6ABP (ABP = Albumin Binding Protein derived from Streptococcal Protein G)

This product is intended to be used as a blocking antigen for antibody competition assays. Any other use of this antigen is done at the risk of the user. The use of this product for commercial production is strictly prohibited. Please contact technical support if you have any questions.

Purity

>80% by SDS-PAGE and Coomassie blue staining

Predicted Molecular Mass

30 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Applications

Antibody Competition (10 - 100 molar excess)

Application Notes

This recombinant antigen is only intended to be used as a blocking agent to confirm antibody specificity with the corresponding antibody, catalog number NBP1-88443.

It is purified by IMAC chromatography, and the expected concentration is greater than 0.5 mg/ml.

For current lot information, including availability, please contact our technical support team click nb-technical@bio-techne.com

Protein / Peptide Type

Recombinant Protein Antigen

Formulation, Preparation and Storage

NBP1-88443PEP
Formulation PBS and 1M Urea, pH 7.4.
Preservative No Preservative
Concentration Please see the vial label for concentration. If unlisted please contact technical services.
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -20C. Avoid freeze-thaw cycles.

Background: GNPTG

GNPTG, also known as N-acetylglucosamine-1-phosphotransferase subunit gamma, is a 305 amino acid that is 34 kDa,; hexamer composed of two alpha, two beta and two gamma subunits, widely expressed; catalyzes the first step in synthesis of a mannose 6-phosphate lysosomal recognition marker, essential for targeting of lysosomal hydrolases to the lysosome. Studies are being performed on the relationship of this protein to mucolipidosis iii gamma, mucolipidosis, mucolipidosis iiic, mucolipidosis ii, dysostosis, short stature, autosomal recessive disease, scoliosis, parkinson's disease, ovarian carcinoma, and retinitis. GNPTG protein involvement has been observed with relation to UPF1 and GNPTAB proteins in the lysosome pathway.

Alternate Names

C16orf27, c316G12.3, CAB56184, GlcNAc-1-phosphotransferase subunit gamma, GNPTAGchromosome 16 open reading frame 27, LP2537, N-acetylglucosamine-1-phosphate transferase, gamma subunit, N-acetylglucosamine-1-phosphotransferase subunit gamma, N-acetylglucosamine-1-phosphotransferase, gamma subunit, RJD9, UDP-N-acetylglucosamine-1-phosphotransferase subunit gamma

Gene Symbol

GNPTG

Additional GNPTG Products

Product Documents for GNPTG Recombinant Protein Antigen

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for GNPTG Recombinant Protein Antigen

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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