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Recombinant Human GP-IX His Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-23083

Novus Biologicals, part of Bio-Techne
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NBP2-23083

Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

Product Specifications

Description

A denatured recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 17-147 of Human GP-IX

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSTKDCPSP CTCRALETMG LWVDCRGHGL TALPALPART RHLLLANNSL QSVPPGAFDH LPQLQTLDVT QNPWHCDCSL TYLRLWLEDR TPEALLQVRC ASPSLAAHGP LGRLTGYQLG SCGWQLQASW VRPG

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

16.8 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Application Notes

Denatured protein is most likely not the best option for functional studies. It is better suited for Western Blot (WB) or imaging assays.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human GP-IX His Protein

SDS-PAGE: Recombinant Human GP-IX His Protein [NBP2-23083]

SDS-PAGE: Recombinant Human GP-IX His Protein [NBP2-23083]

SDS-Page: GP-IX Protein [NBP2-23083]

Formulation, Preparation and Storage

NBP2-23083
Formulation 20mM Tris-HCl buffer (pH 8.0), 0.4M UREA, 10% glycerol
Preservative No Preservative
Concentration 1 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GPIX

GP9 is a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib, a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor. The complete receptor complex includes noncovalent association of the alpha and beta subunits with the protein and platelet glycoprotein V. Defects in this gene are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency. Recombinant human GP9 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Long Name

Glycoprotein IX (platelet)

Alternate Names

CD42a, GP9

Gene Symbol

GP9

Additional GPIX Products

Product Documents for Recombinant Human GP-IX His Protein

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Recombinant Human GP-IX His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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