Recombinant Mouse Histone Deacetylase 8/HDAC8 His Protein

Name: Recombinant Mouse Histone Deacetylase 8/HDAC8 His Protein
Brand: Novus Biologicals
SKU: NBP2-59518

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-59518

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Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

Baculovirus

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all Histone Deacetylase 8/HDAC8 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a C-Terminal His-tag and corresponding to the amino acids 1-377 of Mouse Histone Deacetylase 8/HDAC8

Source: Baculovirus

Amino Acid Sequence: MEMPEEPANS GHSLPPVYIY SPEYVSICDS LVKVPKRASM VHSLIEAYAL HKQMRIVKPK VASMEEMATF HTDAYLQHLQ KVSQEGDEDH PDSIEYGLGY DCPATEGIFD YAAAIGGGTI TAAQCLIDGK CKVAINWSGG WHHAKKDEAS GFCYLNDAVL GILRLRRKFD RILYVDLDLH HGDGVEDAFS FTSKVMTVSL HKFSPGFFPG TGDMSDVGLG KGRYYSVNVP IQDGIQDEKY YHICESVLKE VYQAFNPKAV VLQLGADTIA GDPMCSFNMT PVGIGKCLKY VLQWQLATLI LGGGGYNLAN TARCWTYLTG VILGKTLSSE IPDHEFFTAY GPDYVLEITP SCRPDRNEPH RIQQILNYIK GNLKHVVHHH HHH

Purity

>90%, by SDS-PAGE

Endotoxin Level

< 1.0 EU per 1 microgram of protein (determined by LAL method)

Predicted Molecular Mass

42.5 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Mouse Histone Deacetylase 8/HDAC8 His Protein

SDS-PAGE: Recombinant Mouse Histone Deacetylase 8/HDAC8 His Protein [NBP2-59518]

SDS-Page: Recombinant Mouse Histone Deacetylase 8/HDAC8 Protein [NBP2-59518] - 15% SDS-PAGE (3ug)

Formulation, Preparation and Storage

NBP2-59518

Formulation	PBS (pH 7.4), 10% glycerol
Preservative	No Preservative
Concentration	0.25 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Histone Deacetylase 8/HDAC8

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter.

Alternate Names

HDAC8, HDACL1, RPD3

Gene Symbol

HDAC8

Additional Histone Deacetylase 8/HDAC8 Products

Product Documents for Recombinant Mouse Histone Deacetylase 8/HDAC8 His Protein

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COA

Product Specific Notices for Recombinant Mouse Histone Deacetylase 8/HDAC8 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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