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Recombinant Bovine IL-1 alpha/IL-1F1 Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-62430

Novus Biologicals, part of Bio-Techne
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NBP2-62430

Key Product Details

Source

Pichia pastoris

Accession #

Conjugate

Unconjugated

Applications

ELISA, Functional Assay

Product Specifications

Description

Recombinant bovine interleukin-1 alpha.

Source:Pichia pastoris

Amino Acid Sequence:aa 120-268 of native bovine IL-1a, UniProt P08831

Purity

>95%, by SDS-PAGE

Predicted Molecular Mass

17.1 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Formulation, Preparation and Storage

NBP2-62430
Preparation Method Recombinant protein expressed in Pichia pastoris and purified by ion-exchange chromatography
Formulation PBS
Preservative 10% Trehalose
Concentration Lyoph
Reconstitution Reconstitute with 20 ul sterile PBS containing 0.1% carrier protein. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Gently mix vial after reconstitution.
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -20C. Avoid freeze-thaw cycles.

Background: IL-1 alpha/IL-1F1

Interleukin-1 alpha (IL-1a, lymphocyte activating factor (LAF), hematopoietin-1, endogeneous pyrogen, mononuclear cell factor) is a pleiotropic pro-inflammatory cytokine produced in a variety of cells, including monocytes, macrophages and epithelial cells. It is involved in inflammatory and immune responses and regulation of hematopoiesis. It may therefore be of clinical use following massive immunosuppression and chemotherapy. Recombinant human IL-1a is a single non-glycosylated polypetide chain of 159 amino acids with a MW of 18 kDa. Sequence conservation of the mature protein among various species is 60% -70%, human IL-1 has been found to be biologically active on murine cell lines.

Long Name

Interleukin 1 alpha

Alternate Names

BAF, IL-1A, IL-1F1, IL1, IL1 alpha, IL1A, IL1F1, LAF, LEM

Gene Symbol

IL1A

UniProt

Additional IL-1 alpha/IL-1F1 Products

Product Documents for Recombinant Bovine IL-1 alpha/IL-1F1 Protein

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Recombinant Bovine IL-1 alpha/IL-1F1 Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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