Recombinant Human MAP1 His Protein

Name: Recombinant Human MAP1 His Protein
Brand: Novus Biologicals
SKU: NBP2-23249

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-23249

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Product Specifications
Scientific Data
Preparation & Storage
Background
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Specific Notices

Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all MAP1 Proteins and Enzymes »

Product Specifications

Description

A denatured recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-351 of Human MAP1

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSMTLRLLE DWCRGMDMNP RKALLIAGIS QSCSVAEIEE ALQAGLAPLG EYRLLGRMFR RDENRKVALV GLTAETSHAL VPKEIPGKGG IWRVIFKPPD PDNTFLSRLN EFLAGEGMTV GELSRALGHE NGSLDPEQGM IPEMWAPMLA QALEALQPAL QCLKYKKLRV FSGRESPEPG EEEFGRWMFH TTQMIKAWQV PDVEKRRRLL ESLRGPALDV IRVLKINNPL ITVDECLQAL EEVFGVTDNP RELQVKYLTT YQKDEEKLSA YVLRLEPLLQ KLVQRGAIER DAVNQARLDQ VIAGAVHKTI RRELNLPEDG PAPGFLQLLV LIKDYEAAEE EEALLQAILE GNFT

Purity

>85%, by SDS-PAGE

Predicted Molecular Mass

41.9 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Application Notes

Denatured protein is most likely not the best option for functional studies. It is better suited for Western Blot (WB) or imaging assays.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human MAP1 His Protein

SDS-PAGE: Recombinant Human MAP1 His Protein [NBP2-23249]

SDS-Page: MAP1 Protein [NBP2-23249]

Formulation, Preparation and Storage

NBP2-23249

Formulation	20 mM Tris-HCl buffer (pH8.0), 10% glycerol, 0.4M UREA
Preservative	No Preservative
Concentration	0.5 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MAP1

Modulator of apoptosis 1, also known as MOAP1, belongs to the PNMA family and contains one BH3-like domain and one RASSF1-binding domain. It is required for death receptor-dependent apoptosis. MOAP1 homodimerizes and associates with the proapoptotic Bax and the prosurvival Bcl-2 and Bcl-X(L) of the Bcl-2 family in vitro and in vivo in mammalian cells. These data suggest that MOAP1 mediates apoptosis through a mechanism that involves binding to Bax. Recombinant human MOAP1 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Alternate Names

MAP1, MAP-1PNMA4Paraneoplastic antigen Ma4, modulator of apoptosis 1, paraneoplastic antigen like 4

Gene Symbol

MOAP1

Additional MAP1 Products

Product Documents for Recombinant Human MAP1 His Protein

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COA

Product Specific Notices for Recombinant Human MAP1 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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