Recombinant Human MARCKS like protein His Protein

Name: Recombinant Human MARCKS like protein His Protein
Brand: Novus Biologicals
SKU: NBP2-23217

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-23217

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Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

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Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-195 of Human MARCKS like protein

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSMGSQSSK APRGDVTAEE AAGASPAKAN GQENGHVKSN GDLSPKGEGE SPPVNGTDEA AGATGDAIEP APPSQGAEAK GEVPPKETPK KKKKFSFKKP FKLSGLSFKR NRKEGGGDSS ASSPTEEEQE QGEIGACSDE GTAQEGKAAA TPESQEPQAK GAEASAASEE EAGPQATEPS TPSGPESGPT PASAEQNE

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

21.9 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human MARCKS like protein His Protein

SDS-PAGE: Recombinant Human MARCKS like protein His Protein [NBP2-23217]

SDS-Page: MARCKS like protein Protein [NBP2-23217]

Formulation, Preparation and Storage

NBP2-23217

Formulation	20 mM Tris-HCl buffer (pH 8.0), 0.1 M NaCl, 20% glycerol
Preservative	No Preservative
Concentration	0.25 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MARCKS like protein

MARCKS-related protein, also known as MARCKSL1, is a member of MARCKS family of PKC substrate. It is widely used in the signal transduction studies as an indicator of PKC activation. Expressed in a variety of tissues with highest levels found in testis and uterus, MARCKSL1 participates in the coordination of membrane-cytoskeletal signaling events, including secretion, migration, phagocytosis and cell adhesion. Additionally, MARCKSL1 functions as a regulator of Integrin activation and is thought to regulate Integrin-dependent signal transduction pathways, especially those involved in macrophage spreading. Recombinant human MARCKSL1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Alternate Names

F52, MacMARCKS, Mac-MARCKS, Macrophage myristoylated alanine-rich C kinase substrate, MARCKS-like 1, MARCKS-like protein 1, MARCKS-related protein, MLP1, MLPMARCKS-like protein, MRPMACMARCKS

Gene Symbol

MARCKSL1

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COA

Product Specific Notices for Recombinant Human MARCKS like protein His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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