Recombinant Human MMP-10 His Protein

Name: Recombinant Human MMP-10 His Protein
Brand: Novus Biologicals
SKU: NBP2-51553

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-51553

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Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all MMP-10 Proteins and Enzymes »

Product Specifications

Description

A denatured recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 99-476 of Human MMP-10

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSFSSFPGM PKWRKTHLTY RIVNYTPDLP RDAVDSAIEK ALKVWEEVTP LTFSRLYEGE ADIMISFAVK EHGDFYSFDG PGHSLAHAYP PGPGLYGDIH FDDDEKWTED ASGTNLFLVA AHELGHSLGL FHSANTEALM YPLYNSFTEL AQFRLSQDDV NGIQSLYGPP PASTEEPLVP TKSVPSGSEM PAKCDPALSF DAISTLRGEY LFFKDRYFWR RSHWNPEPEF HLISAFWPSL PSYLDAAYEV NSRDTVFIFK GNEFWAIRGN EVQAGYPRGI HTLGFPPTIR KIDAAVSDKE KKKTYFFAAD KYWRFDENSQ SMEQGFPRLI ADDFPGVEPK VDAVLQAFGF FYFFSGSSQF EFDPNARMVT HILKSNSWLH C

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

45.4 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Application Notes

Denatured protein is most likely not the best option for functional studies. It is better suited for Western Blot (WB) or imaging assays.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human MMP-10 His Protein

SDS-PAGE: Recombinant Human MMP-10 His Protein [NBP2-51553]

SDS-Page: Recombinant Human MMP-10 Protein [NBP2-51553] - 15% SDS Page (3 ug)

Formulation, Preparation and Storage

NBP2-51553

Formulation	20 mM Tris-HCl buffer (pH 8.0), 0.4M UREA, 10% glycerol
Preservative	No Preservative
Concentration	0.5 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MMP-10

Matrix metalloproteinases belong to a family of proteases that are essential for the breakdown of extracellular matrix (ECM), thus they play an important role in apoptosis, and tumor cell growth, invasion, metastasis, as well as in angiogenesis and wound healing. Most of the MMP's contain a common domain structures, which include a signal sequence, a propeptide, a catalytic domain and a hemopexin-like (Hpx) domain. MMP10 belongs to the Stromelysin group of proteases. Stromelysins degrade ECM proteoglycans, laminin, fibronectin and gelatin.

Long Name

Matrix Metalloproteinase 10

Alternate Names

MMP10, Stromelysin 2

Gene Symbol

MMP10

Additional MMP-10 Products

Product Documents for Recombinant Human MMP-10 His Protein

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COA

Product Specific Notices for Recombinant Human MMP-10 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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