Recombinant Human NRAMP1/SLC11A1 GST (N-Term) Protein

Name: Recombinant Human NRAMP1/SLC11A1 GST (N-Term) Protein
Brand: Novus Biologicals
SKU: H00006556-Q01

Novus Biologicals, part of Bio-Techne | Catalog # H00006556-Q01

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Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

Wheat germ

Tag

GST (N-Term)

Conjugate

Unconjugated

Applications

ELISA, Affinity Purification, Microarray, SDS-PAGE, Western Blot

View all NRAMP1/SLC11A1 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-terminal GST tag corresponding to the amino acid sequence 308-350 of Human NRAMP1/SLC11A1

Source: Wheat Germ (in vitro)

Amino Acid Sequence: QAFYQKTNQAAFNICANSSLHDYAKIFPMNNATVAVDIYQGGV

Purity

>80% by SDS-PAGE and Coomassie blue staining

Predicted Molecular Mass

30.47 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Activity

This protein was produced in an in vitro wheat germ expression system that should preserve correct conformational folding that is necessary for biological function. While it is possible that this protein could display some level of activity, the functionality of this protein has not been explicitly measured or validated.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human NRAMP1/SLC11A1 GST (N-Term) Protein

SDS-PAGE: Recombinant Human NRAMP1/SLC11A1 GST (N-Term) Protein [H00006556-Q01]

SDS-Page: Recombinant Human NRAMP1/SLC11A1 Protein [H00006556-Q01] - 12.5% SDS-PAGE Stained with Coomassie Blue.

Formulation, Preparation and Storage

H00006556-Q01

Preparation Method	in vitro wheat germ expression system
Formulation	50 mM Tris-HCI, 10 mM reduced Glutathione, pH 8.0 in the elution buffer.
Preservative	No Preservative
Concentration	Please see the vial label for concentration. If unlisted please contact technical services.
Shipping	The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at -80C. Avoid freeze-thaw cycles.

Background: NRAMP1/SLC11A1

This gene is a member of the solute carrier family 11 (proton-coupled divalent metal ion transporters) family and encodes a multi-pass membrane protein. The protein functions as a divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Mutations in this gene have been associated with susceptibility to infectious diseases such as tuberculosis and leprosy, and inflammatory diseases such as rheumatoid arthritis and Crohn disease. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined. [provided by RefSeq]

Long Name

Natural Resistance-associated Macrophage Protein 1

Alternate Names

LSH, SLC11A1

Gene Symbol

SLC11A1

Additional NRAMP1/SLC11A1 Products

Product Documents for Recombinant Human NRAMP1/SLC11A1 GST (N-Term) Protein

Product Datasheets

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COA

SDS

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Product Specific Notices for Recombinant Human NRAMP1/SLC11A1 GST (N-Term) Protein

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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