Recombinant Human NRG4 His Protein

Name: Recombinant Human NRG4 His Protein
Brand: Novus Biologicals
SKU: NBP2-23278

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-23278

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Technical Data
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Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all NRG4 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-61 of Human NRG4

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSMPTDHEE PCGPSHKSFC LNGGLCYVIP TIPSPFCRCV ENYTGARCEE VFLPGSSIQT KSNL

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

9.1 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human NRG4 His Protein

SDS-PAGE: Recombinant Human NRG4 His Protein [NBP2-23278]

SDS-Page: NRG4 Protein [NBP2-23278]

Formulation, Preparation and Storage

NBP2-23278

Formulation	20 mM Tris-HCl buffer (pH8.0), 30% glycerol, 0.15 M NaCl, 1 mM DTT
Preservative	No Preservative
Concentration	0.25 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: NRG4

NRG4 belongs to the neuregulin family and contains 1 EGF-like domain. The protein is low affinity ligand for the ERBB4 tyrosine kinase receptor. It concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. NRG4 does not bind to the ERBB1, ERBB2 and ERBB3 receptors. Recombinant human NRG4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Alternate Names

DKFZp779N0541, DKFZp779N1944, heregulin 4, HRG4pro-NRG4, neuregulin 4, pro-neuregulin-4, membrane-bound isoform, Pro-NRG4

Gene Symbol

NRG4

Additional NRG4 Products

Product Documents for Recombinant Human NRG4 His Protein

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COA

Product Specific Notices for Recombinant Human NRG4 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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