Recombinant Human p18INK4c/CDKN2C His Protein

Name: Recombinant Human p18INK4c/CDKN2C His Protein
Brand: Novus Biologicals
SKU: NBP1-78876

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-78876

Submit a review

Product Datasheet / COA

100% Guarantee

Technical Data
Citations & Reviews

Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all p18INK4c/CDKN2C Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-168 of Human p18INK4c/CDKN2C

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMAEPWG NELASAAARG DLEQLTSLLQ NNVNVNAQNG FGRTALQVMK LGNPEIARRL LLRGANPDLK DRTGFAVIHD AARAGFLDTL QTLLEFQADV NIEDNEGNLP LHLAAKEGHL RVVEFLVKHT ASNVGHRNHK GDTACDLARL YGRNEVVSLM QANGAGGATN LQ

Purity

>95%, by SDS-PAGE

Predicted Molecular Mass

20.7 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human p18INK4c/CDKN2C His Protein

SDS-PAGE: Recombinant Human p18INK4c/CDKN2C His Protein [NBP1-78876]

SDS-Page: Recombinant Human p18INK4c/CDKN2C Protein [NBP1-78876] - 15% SDS-PAGE (3ug)

Formulation, Preparation and Storage

NBP1-78876

Formulation	20 mM Tris-HCl buffer (pH 8.0), 2 mM DTT, 10% glycerol, 200 mM NaCl
Preservative	No Preservative
Concentration	0.5 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: p18INK4c/CDKN2C

CDKN2C (Cyclin-dependent kinase 4 inhibitor C ) belongs to the CDKN2 cyclin-dependent kinase inhibitor family. It has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. And this protein suppresses the cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Recombinant human CDKN2C protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Long Name

p18 Cyclin Dependent Kinase 4 Inhibitor 2C

Alternate Names

CDKN2C, p18-INK6

Gene Symbol

CDKN2C

Additional p18INK4c/CDKN2C Products

Product Documents for Recombinant Human p18INK4c/CDKN2C His Protein

Product Datasheets

Download Product Datasheets

COA

Product Specific Notices for Recombinant Human p18INK4c/CDKN2C His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

Citations
Reviews