PGD2 Synthase/PTGDS Antibody Blocking Peptide

Novus Biologicals, part of Bio-Techne | Catalog # NB110-59911PEP

Novus Biologicals, part of Bio-Techne
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NB110-59911PEP
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Key Product Details

Conjugate

Unconjugated

Applications

Antibody Competition

View all PGD2 Synthase/PTGDS Proteins and Enzymes »

Product Specifications

Description

A PTGDS antibody blocking peptide.

Application Notes

This peptide is useful as a blocking peptide for NB110-59911. For further blocking peptide related protocol, click here.

Specificity

This peptide is specific for NB110-59911 only.

Protein / Peptide Type

Antibody Blocking Peptide

Formulation, Preparation and Storage

NB110-59911PEP
Formulation Peptide dissolved in dH2O. Contains no BSA.
Preservative No Preservative
Concentration 1.0 mg/ml
Shipping The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -80C. Avoid freeze-thaw cycles.

Background: PGD2 Synthase/PTGDS

Prostaglandin D Synthase (PTGDS), is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. PTGDS has also been implicated in the development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-testis barrier. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement (NREM) sleep. It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system. PTGDS is the most abundant protein in the cerebral spinal fluid and recent evidence suggests that PTGDS acts as a Beta-Amyloid chaperone and may have a role in the deposition of amyloid-b plaques in Alzheimer's disease.

Long Name

Prostaglandin D2 Synthase

Alternate Names

Cerebrin-28, PDS, PGD2, PGDS2, PH2DISO, PTGDS

Gene Symbol

PTGDS

Additional PGD2 Synthase/PTGDS Products

Product Documents for PGD2 Synthase/PTGDS Antibody Blocking Peptide

Product Datasheets

Certificate of Analysis

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Product Specific Notices for PGD2 Synthase/PTGDS Antibody Blocking Peptide

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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