Recombinant Human PGD2 Synthase/PTGDS His Protein

Name: Recombinant Human PGD2 Synthase/PTGDS His Protein
Brand: Novus Biologicals
SKU: NBP1-51078

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-51078

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Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all PGD2 Synthase/PTGDS Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 23-190 of Human PGD2 Synthase/PTGDS

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MAPEAQVSVQ PNFQQDKFLG RWFSAGLASN SSWLREKKAA LSMCKSVVAP ATDGGLNLTS TFLRKNQCET RTMLLQPAGS LGSYSYRSPH WGSTYSVSVV ETDYDQYALL YSQGSKGPGE DFRMATLYSR TQTPRAELKE KFTAFCKAQG FTEDTIVFLP QTDKCMTEQ

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

20.9 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human PGD2 Synthase/PTGDS His Protein

SDS-PAGE: Recombinant Human PGD2 Synthase/PTGDS His Protein [NBP1-51078]

SDS-Page: Recombinant Human PGD2 Synthase/PTGDS Protein [NBP1-51078] - 15% SDS-PAGE

Formulation, Preparation and Storage

NBP1-51078

Formulation	20 mM Tris-HCl buffer (pH 8.0), 1 mM DTT, 30% glycerol, 1 mM EDTA, 0.1 M NaCl
Preservative	No Preservative
Concentration	1 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PGD2 Synthase/PTGDS

Prostaglandin-H2 D-isomerase, also known as PTGDS, is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system. PTGDS is the most abundant protein in the cerebral spinal fluid and recent evidence suggests that PTGDS acts as a beta-amyloid chaperone and may have a role in the deposition of Ab plaques in Alzheimer's disease. Recombinant human PTGDS protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Long Name

Prostaglandin D2 Synthase

Alternate Names

Cerebrin-28, PDS, PGD2, PGDS2, PH2DISO, PTGDS

Gene Symbol

PTGDS

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COA

Product Specific Notices for Recombinant Human PGD2 Synthase/PTGDS His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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