Recombinant Human PIN/DLC8 His Protein

Name: Recombinant Human PIN/DLC8 His Protein
Brand: Novus Biologicals
SKU: NBP1-49430

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-49430

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Technical Data
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Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

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Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-89 of Human PIN/DLC8

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MCDRKAVIKN ADMSEEMQQD SVECATQALE KYNIEKDIAA HIKKEFDKKY NPTWHCIVGR NFGSYVTHET KHFIYFYLGQ VAILLFKSG

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

12.5 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human PIN/DLC8 His Protein

SDS-PAGE: Recombinant Human PIN/DLC8 His Protein [NBP1-49430]

SDS-Page: Recombinant Human PIN/DLC8 Protein [NBP1-49430] - 15 % SDS-PAGE (3ug)

Formulation, Preparation and Storage

NBP1-49430

Formulation	20 mM Tris-HCl buffer (pH8.0), 0.2 M NaCl, 1 mM DTT, 10% glycerol
Preservative	No Preservative
Concentration	1 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PIN

DYNLL1, also known as DLC8 or PIN (protein inhibitor of neuronal nitric oxide synthase), has been identified as a protein that interacts with NOS1 resulting in NOS1 inhibition. Binding of this protein destabilizes NOS1(Neuronal nitric oxide synthase) dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. DYNLL1 is a ubiquitously expressed protein that exhibits high expression in testis and moderate expression in brain. Recombinant human DYNLL1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Long Name

Protein Inhibitor of Neuronal Nitric Oxide Synthase

Alternate Names

DLC1, DLC8, DNCL1, DNCLC1, DYNLL1, LC8a

Gene Symbol

DYNLL1

Additional PIN Products

Product Documents for Recombinant Human PIN/DLC8 His Protein

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COA

Product Specific Notices for Recombinant Human PIN/DLC8 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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