Recombinant Human PIPPIN His Protein

Name: Recombinant Human PIPPIN His Protein
Brand: Novus Biologicals
SKU: NBP2-22792

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-22792

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Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all PIPPIN Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-153 of Human PIPPIN

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSMTSESTS PPVVPPLHSP KSPVWPTFPF HREGSRVWER GGVPPRDLPS PLPTKRTRTY SATARASAGP VFKGVCKQFS RSQGHGFITP ENGSEDIFVH VSDIEGEYVP VEGDEVTYKM CPIPPKNQKF QAVEVVLTQL APHTPHETWS GQVVGS

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

19.2 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human PIPPIN His Protein

SDS-PAGE: Recombinant Human PIPPIN His Protein [NBP2-22792]

SDS-Page: PIPPIN Protein [NBP2-22792]

Formulation, Preparation and Storage

NBP2-22792

Formulation	20 mM Tris-HCl buffer (pH8.0), 10% glycerol, 0.1 M NaCl
Preservative	No Preservative
Concentration	0.5 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PIPPIN

CSDC2, as known as cold shock domain-containing protein C2, is RNA-binding factor which binds specifically to the very 3'-UTR ends of both histone H1 and H3.3 mRNAs, encompassing the polyadenylation signal. The cold shock domain containing proteins (CSDPs) are one group of the evolutionarily conserved nucleic acid-binding proteins widely distributed in bacteria, plants, animals, and involved in various cellular processes, including adaptation to low temperature, cellular growth, nutrient stress and stationary phase. It may play a central role in the negative regulation of histone variant synthesis in the developing brain. Recombinant human CSDC2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Alternate Names

cold shock domain containing C2, RNA binding, cold shock domain-containing protein C2, dJ347H13.2, PIPPIN, RNA-binding protein PIPPin

Gene Symbol

CSDC2

Additional PIPPIN Products

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COA

Product Specific Notices for Recombinant Human PIPPIN His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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