Recombinant Human PTHLH/PTHrP Protein

Name: Recombinant Human PTHLH/PTHrP Protein
Brand: Novus Biologicals
SKU: NBP2-35224

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-35224

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Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

E. coli

Accession #

P12272

Conjugate

Unconjugated

Applications

SDS-PAGE

View all PTHLH/PTHrP Proteins and Enzymes »

Product Specifications

Description

A single non-glycosylated polypeptide chain containing 86 amino acids corresponding to PTHLH/PTHrP Source: E. coli

Uniprot ID: P12272

Amino Acid Sequence: AVSEHQLLHD KGKSIQDLRR RFFLHHLIAE IHTAEIRATS EVSPNSKPSP NTKNHPVRFG SDDEGRYLTQ ETNKVETYKE QPLKTP

This lyophilized preparation is stable at 2-8 degrees C, but should be kept at -20 degrees C for long term storage, preferably desiccated. Upon reconstitution, the preparation is most stable at -20 to -80 degrees C, and can be stored for one week at 2-8 degrees C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 degrees C to -80 degrees C. Avoid repeated freeze/thaw cycles.

Purity

> 98 % pure by SDS-PAGE and HPLC

Endotoxin Level

Less than 0.1 EU/ug of PTHLH/PTHrP as determined by LAL method.

Predicted Molecular Mass

9.9 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human PTHLH/PTHrP Protein

SDS-PAGE: Recombinant Human PTHLH/PTHrP Protein [NBP2-35224]

SDS-Page: Human PTHLH/PTHrP Protein [NBP2-35224]

Formulation, Preparation and Storage

NBP2-35224

Formulation	Lyophilized from a 0.2 um filtered concentrated solution in 10 mM PB, pH 6.0, 300 mM NaCl.
Preservative	No Preservative
Concentration	Lyoph
Reconstitution	Recommended to centrifuge prior to opening. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/mL. Apportion stock solutions into working aliquots and store at
Format	Carrier-Free
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at -20 to -70C as supplied. After reconstitution, store at 2 to 8C for 1 month and at -20 to -70C for long term storage. Avoid repeated freeze-thaw cycles.

Background: PTHLH/PTHrP

PTHLH (PTHrP), also named parathyroid hormone-related protein, is belonging to the parathyroid hormone family. PTHLH (PTHrP) is expressed in cancer cells (breast cancer, certain types of lung cancer including squamous cell lung carcinoma). The receptor for PTHrP is PTHR1. PTHLH (PTHrP) plays a central role in regulating the hypercalcemia. Recombinant human PTHLH (PTHrP) is a 9.9 kDa linear polypeptide of 86 amino acid residues and it shares 86 % a.a. identity with murine PTHLH.

Long Name

Parathyroid Hormone-like Hormone

Alternate Names

BDE2, HHM, Osteostatin, PTHRP

Gene Symbol

PTHLH

UniProt