Recombinant Human PTPMT1 His Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-78852

Novus Biologicals, part of Bio-Techne
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NBP1-78852-0.5mg
NBP1-78852-100ug
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Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all PTPMT1 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 28-201 of Human PTPMT1

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMKVPGR AHRDWYHRID PTVLLGALPL RSLTRQLVQD ENVRGVITMN EEYETRFLCN SSQEWKRLGV EQLRLSTVDM TGIPTLDNLQ KGVQFALKYQ SLGQCVYVHC KAGRSRSATM VAAYLIQVHK WSPEEAVRAI AKIRSYIHIR PGQLDVLKEF HKQITARATK DGTFVISKT

Purity

>95%, by SDS-PAGE

Predicted Molecular Mass

22.5 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human PTPMT1 His Protein

SDS-PAGE: Recombinant Human PTPMT1 His Protein [NBP1-78852]

SDS-PAGE: Recombinant Human PTPMT1 His Protein [NBP1-78852]

SDS-Page: Recombinant Human PTPMT1 Protein [NBP1-78852] - 15% SDS-PAGE (3ug)
SDS-PAGE: Recombinant Human PTPMT1 His Protein [NBP1-78852]

SDS-PAGE: Recombinant Human PTPMT1 His Protein [NBP1-78852]

SDS-Page: Recombinant Human PTPMT1 Protein [NBP1-78852] - 3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.

Formulation, Preparation and Storage

NBP1-78852
Formulation 20 mM Tris-HCl buffer (pH 8.0), 10% glycerol, 1 mM DTT, 0.15 M NaCl
Preservative No Preservative
Concentration 1 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PTPMT1

PTPMT1 (protein tyrosine phosphatase mitochondrial 1), also known as MOSP or PLIP (phosphoinositide lipid phosphatase) and previously known as DUSP23, is a widely expressed PTP membrane protein with high expression levels in pancreatic beta cells. This protein exclusively localizes to the matrix face of the inner membrane of the mitochondrion. It is responsible for dephosphorylating mitochondrial proteins and therefore plays a significant role in the production of ATP and secretion of insulin. For its substrate, PTPMT1 displays a specific preference for the lipid signaling molecule phosphatidylinositol 5-phosphate. Recombinant human PTPMT1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Alternate Names

DUSP23, EC 3.1.3.16, EC 3.1.3.48, FLJ46081, MOSPNB4 apoptosis/differentiation related protein, Phosphoinositide lipid phosphatase, PLIPprotein-tyrosine phosphatase mitochondrial 1, protein tyrosine phosphatase, mitochondrial 1, PTEN-like phosphatase

Gene Symbol

PTPMT1

Additional PTPMT1 Products

Product Documents for Recombinant Human PTPMT1 His Protein

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Recombinant Human PTPMT1 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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