Recombinant Human Annexin A10 Protein, CF

R&D Systems, part of Bio-Techne | Catalog # 9416-AN

R&D Systems, part of Bio-Techne
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9416-AN-050
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Key Product Details

Source

E. coli

Accession #

Q9UJ72

Conjugate

Unconjugated

View all Annexin A10 Proteins and Enzymes »

Product Specifications

Source

E. coli-derived human Annexin A10 protein
Met1-Tyr324, with a C-terminal 6-His tag

Purity

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

Endotoxin Level

<0.10 EU per 1 μg of the protein by the LAL method.

N-terminal Sequence Analysis

Met1

Predicted Molecular Mass

38 kDa

SDS-PAGE

34 kDa, reducing conditions

Activity

Bioassay data are not available.

Formulation, Preparation and Storage

9416-AN
Formulation Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution
Reconstitute at 250 μg/mL in PBS.

Reconstitution Buffer Available:
Size / Price
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Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Annexin A10

Human Annexin A10 (ANXA10), also known as Annexin 10 or Annexin-14, is a 37 kDa member of the Annexin family (1), which are calcium-dependent phospholipid-binding proteins preferentially being located on the cytosolic face of the plasma membrane. The Annexins consist of a unique N-terminal domain followed by a homologous C-terminal core domain containing the phospholipid-binding sites. The C-terminal domain is comprised of four 60‑70 aa annexin repeats which form a tightly packed disc known as the annexin domain. Members of the Annexin family play a role in cytoskeletal interactions, phospholipase inhibition, regulation of cellular growth, and intracellular signal transduction pathways (2). Human Annexin A10 shares approximately 89% and 88% aa sequence identity with mouse and rat Annexin A10 respectively.

References

  1. Morgan, R. et al. (1999) Genomics 60:40.
  2. Gerke, V. et al. (2005) Nat. Rev. Mol. Cell Biol. 6:449.

Alternate Names

ANX14, ANXA10

Entrez Gene IDs

11199 (Human)

Gene Symbol

ANXA10

UniProt

Q9UJ72

Additional Annexin A10 Products

Product Documents for Recombinant Human Annexin A10 Protein, CF

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Recombinant Human Annexin A10 Protein, CF

For research use only

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