Recombinant Human beta APP+1 Western Blot Standard Protein

R&D Systems, part of Bio-Techne | Catalog # WBC012

R&D Systems, part of Bio-Techne
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WBC012
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Key Product Details

Source

E. coli

Conjugate

Unconjugated

Applications

Western Blot

View all APP+1 Proteins and Enzymes »

Formulation, Preparation and Storage

WBC012
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: APP+1

Amyloid Precursor Protein (APP) is a type I transmembrane protein that is ubiquitously expressed on cell surfaces. It undergoes complex proteolytic processing and is cleaved by alpha-, beta-, and gamma-Secretases to generate soluble APP alpha, soluble APP beta, and Amyloid beta (A beta) fragments of several lengths. One of these fragments, A beta 42, generated by beta- and gamma-Secretase activities, has been implicated in Alzheimer's disease. Aberrantly high levels of this peptide form and accumulate in the brains of Alzheimer's disease patients to create the senile plaques characteristic of the disease.

Long Name

Amyloid Precursor Protein +1 Frameshift Mutant

Entrez Gene IDs

351 (Human); 11820 (Mouse)

Gene Symbol

APP

Additional APP+1 Products

Product Documents for Recombinant Human beta APP+1 Western Blot Standard Protein

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Recombinant Human beta APP+1 Western Blot Standard Protein

For research use only

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