Recombinant Human FLIP Western Blot Standard Protein

Name: Recombinant Human FLIP Western Blot Standard Protein
Brand: R&D Systems
SKU: WBC001

R&D Systems, part of Bio-Techne | Catalog # WBC001

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Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

E. coli

Conjugate

Unconjugated

Applications

Western Blot

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Formulation, Preparation and Storage

WBC001

Shipping	The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: FLIP

FLIP (Flice-like Inhibitory Protein), also known as I-FLICE, CASPER, and FLAME-1, is an apoptosis inhibitory protein with architecture similar to that of Caspases-8 and -10. Both of the FLIP isoforms, Long (L) and Short (S), contain two death effector domains (DED). FLIP(L) has a C-terminal Caspase-like protease domain which lacks both a catalytic active site and residues that form a substrate-binding pocket. FLIP(S) and FLIP(L) interact with the adaptor molecule FADD, and potently inhibit apoptosis initiated by Fas Ligand/TNF signaling pathways.

Long Name

FLICE Inhibitory Proteins

Alternate Names

CASPER, CFLAR, FLAME-1, I-FLICE

Entrez Gene IDs

8837 (Human); 12633 (Mouse)

Gene Symbol

CFLAR

Additional FLIP Products

Product Documents for Recombinant Human FLIP Western Blot Standard Protein

Product Datasheets

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COA

SDS

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Product Specific Notices for Recombinant Human FLIP Western Blot Standard Protein

For research use only

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