Recombinant Mouse CLEC-2/CLEC1B Protein, CF
R&D Systems, part of Bio-Techne | Catalog # 9117-CL
Key Product Details
Product Specifications
Source
Mouse myeloma cell line, NS0-derived mouse CLEC-2/CLEC1B protein
Met53-Leu229, with an N-terminal 6-His tag
Met53-Leu229, with an N-terminal 6-His tag
Purity
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
Endotoxin Level
<0.10 EU per 1 μg of the protein by the LAL method.
N-terminal Sequence Analysis
His
Predicted Molecular Mass
21 kDa
SDS-PAGE
24-39 kDa, reducing conditions
Activity
Measured by its binding ability in a functional ELISA.
When Recombinant Mouse Podoplanin Fc Chimera (Catalog # 3244-PL) is coated at 1.0 µg/mL (100 μL/well), Recombinant Mouse CLEC-2/CLEC1B binds with a typical ED50 of 0.1-0.5 μg/mL.
When Recombinant Mouse Podoplanin Fc Chimera (Catalog # 3244-PL) is coated at 1.0 µg/mL (100 μL/well), Recombinant Mouse CLEC-2/CLEC1B binds with a typical ED50 of 0.1-0.5 μg/mL.
Scientific Data Images for Recombinant Mouse CLEC-2/CLEC1B Protein, CF
Recombinant Mouse CLEC-2/CLEC1B Protein Bioactivity
When Recombinant Mouse Podoplanin Fc Chimera (Catalog # 3244-PL) is coated at 1.0 µg/mL, Recombinant Mouse CLEC-2/CLEC1B (Catalog # 9117-CL) binds with a typical ED50 of 0.1-0.5 µg/mL.Formulation, Preparation and Storage
9117-CL
Formulation | Lyophilized from a 0.2 μm filtered solution in PBS. |
Reconstitution |
Reconstitute at 100 μg/mL in PBS.
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Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
Stability & Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
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Background: CLEC-2/CLEC1B
References
- Lee, R.H. and W. Bergmeier (2016) J. Thromb. Haemost. Epub PMID 26749528.
- Suzuki-Inoue, K. et al. (2006) Blood 107:542.
- Chaipan, C. et al. (2006) J. Virol. 80:8951.
- Gitz, E. et al. (2014) Blood 124:2262.
- Suzuki-Inoue, K. et al. (2007) J. Biol. Chem. 282:25993.
- Christou, C.M. et al. (2008) Biochem. J. 411:133.
- Herzog, B.H. et al. (2013) Nature 502:105.
- Sweet, D.T. et al. (2015) J. Clin. Invest. 125:2995.
- Hess, P.R. et al. (2014) J. Clin. Invest. 124:273.
- Osada, M. et al. (2012) J. Biol. Chem. 287:22241.
- Manne, B.K. et al. (2013) J. Biol. Chem. 288:7717.
- Wu, X. et al. (2015) EbioMedicine 2:214.
Long Name
C-type Lectin-like Receptor 2
Alternate Names
CLEC1B, CLEC2
Gene Symbol
CLEC1B
UniProt
Additional CLEC-2/CLEC1B Products
Product Documents for Recombinant Mouse CLEC-2/CLEC1B Protein, CF
Product Specific Notices for Recombinant Mouse CLEC-2/CLEC1B Protein, CF
For research use only
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